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Fermented Wheat Germ

12 bytes added, 08:14, 29 November 2013
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Cancer : New research has confirmed that fermented wheat germ – especially using sourdough fermentation methods – is a viable cancer treatment, able to halt the growth of cancer cells. The new research, from Italy’s University of Bari and Germany’s Martin Luther University, screened over 40 fermenting bacteria types and tested wheat germ fermented using traditional sourdough methods against raw wheat germ. The laboratory research then tested these against multiple human cancer cell lines. They found that while the raw wheat germ had no anticancer potential, the fermented wheat germs showed significant inhibition of cancer cell growth.The researchers commented that: “These results are comparable to those found for other well-known pharmaceutical preparations…” There was a variance between the extent of cancer inhibition among the types of cancer tested, which included ovarian cancer, colon cancer and germ cell tumors. The researchers found that the fermented wheat germs inhibited ovarian cancer cells the most between the three, but all three were inhibited by the fermented line. The research also found that two of the bacteria used in fermentation – bacteria normally found among fermented wheat germ – were especially productive because they produced an enzyme called beta-glucosidase. The two highest beta-glucosidase producing fermentation processes utilized the bacteria species Lactobacillus plantarum and Lactobacillus rossiae.
==References==
*''*Rizzello CG, Mueller T, Coda R, Reipsch F, Nionelli L, Curiel JA, Gobbetti M. Synthesis of 2-methoxy benzoquinone and 2,6-dimethoxybenzoquinone by selected lactic acid bacteria during sourdough fermentation of wheat germ. Microb Cell Fact. 2013 Nov 11;12(1):105.''*''Judson PL, Al Sawah E, Marchion DC, Xiong Y, Bicaku E, Bou Zgheib N, Chon HS, Stickles XB, Hakam A, Wenham RM, Apte SM, Gonzalez-Bosquet J, Chen DT, Lancaster JM. Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity. Int J Gynecol Cancer. 2012 Jul;22(6):960-7. doi: 10.1097/IGC.0b013e318258509d.''*''Demidov LV, Manziuk LV, Kharkevitch GY, Pirogova NA, Artamonova EV. Adjuvant fermented wheat germ extract (Avemar) nutraceutical improves survival of high-risk skin melanoma patients: a randomized, pilot, phase II clinical study with a 7-year follow-up. Cancer Biother Radiopharm. 2008 Aug;23(4):477-82. doi:10.1089/cbr.2008.0486.''*''Comin-Anduix B, Boros LG, Marin S, Boren J, Callol-Massot C, Centelles JJ, Torres JL, Agell N, Bassilian S, Cascante M. Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. J Biol Chem. 2002 Nov 29;277(48):46408-14.''
[[Category:Treatments]]
[[Category:herbal medicine]]
[[Category:Alternative Cancer Treatments]]
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