* Liver disease: Alkanna contains chemicals called hepatotoxic pyrrolizidine alkaloids (PAs). These chemicals harm the liver, making existing liver disease worse.
==Benefits and uses of Alkanna are==
The root is antibacterial, antipruritic, astringent and vulnerary.
* It is used externally in the treatment of varicose veins, indolent ulcers, bed sores and itching rashes.
* Despite serious safety concerns, people use alkanna for diarrhea and stomach ulcers.
* Alkanna is sometimes applied directly to the skin to heal wounds and treat skin diseases.
* Medications that increase the breakdown of other medications by the liver (Cytochrome P450 3A4 (CYP3A4) inducers) interacts with ALKANNA
== References ==
[[Category:Treatments]]
[[Category:herbal medicine]]