[[File:Peganum harmala.jpeg|thumb|Alt=Peganum harmala|300px|left|Peganum harmala]]
Other Names : Peganum harmala, Wild rue, African rue, esfand, espand, harmel, rue sauvage, alharma, gamarza, སེ པན Sepan Marathi: Harmala, Harmal, Isband, Isband Lahouri, eeme goranti; haramala, soma, simaiyalavinai, simaiyaravandi, cimai alavanam, shima-goranti-vittulu, Ispand, Aspand, Tukhm kunch hi maing, 骆驼 蓬 luo tuo peng, Luo Tuo Peng Zi, 骆驼蓬子, Seed Of Common Peganum, .
==Special Precautions of Syrian Rue==
* In addition to all therapeutic effects of P. harmala, there have been several reports of human[79] and animal[68] intoxications induced by this plant. There are also experimental studies indicating P. harmala toxicity.[6,7] In an in vitro study, intrapretoneal administration of three different extracts of P. harmala at a dose of 50 mg/kg body weight induced sympthoms such as: Abdominal writhing, body tremors and slight decrease in locomotor activity,[21] while oral administration of these extracts showed no toxicity. There have been also the same symptoms reported in different human cases[2,6,80] following ingestions of P. haramala seed extract or infusion including: Neuro-sensorial symptoms, visual hallucination, slight elevation of body temperature, cardio-vascular disorder such as bradycardia and low blood pressure, psychomotor agitation, diffuse tremors, ataxia and vomiting. Despite animal intoxications in almost all of human cases, P. harmala poisonings were relieved in a few hours.[6] P. harmala extract is toxic at high-doses[7,77,81,82] and can cause paralysis, liver degeneration, spongiform changes in the central nervous system,[83] euphoria, convulsions, digestive problems (nausea, vomiting), hypothermia and bradycardia.[2,6,68,80] However, therapeutic doses have been reported to be safe in a rodent model.[54]
[[Category:Treatments]]
[[Category:Herbal medicine]]
[[Category:Anti-angiogenic]]