Changes

* Combination with [[Saw Palmetto]] : In Europe, nettle root extract is often combined with saw palmetto. This is a potent combination, as the nettle root acts primarily through the alternative signaling pathway in the cells of the prostate, and the saw palmetto acts on the first signaling pathway that inhibits DHT activity. The nettle root mainly affects the estrogen side of the hypertrophy, while the saw palmetto mainly affects the androgen side. Both plants have an anti-inflammatory effect. A double-blind randomized study compared the effects of the combination of nettle root with saw palmetto and that of finasteride, a classic drug. The study was conducted in 543 patients with benign stage I or II prostate hypertrophy. Both treatments were found to be equally effective on the different parameters: urine flow, duration of voiding, IPSS scores and evaluation of the patients' quality of life. The effectiveness of both treatments increased with increasing duration of treatment. For example, the mean IPSS score dropped from 11.8 to 8 after four weeks of treatment with the plant extract. After 48 weeks, the score dropped to 6.5. In the group that took finasteride, the score dropped from 11.8 to 8 after 24 weeks. After 48 weeks, the score had dropped to 6.2.12 . In a large observational study, 419 urologists followed a total of 2030 patients with mild to moderately advanced benign prostatic hypertrophy. All patients received a mix of saw palmetto and nettle root for 12 weeks. Improvements were noted at the end of the study, namely: maximum urine flow was increased by 25.8%, mean urine flow was increased by 29%, urine residue after urination was decreased by 44.7%, nocturnal voidings by 50 .4% and the dysuria (problems with urination) with 62.1%. 86% of the patients showed improvements.

Main Combinations :

[[Category:Treatments]]

[[Category:herbal medicine]]