Waldheimia glabra

Health Benefits and Uses of Waldheimia glabra

W. glabra was traditionally believed to prevent colds and fever by local people in Tibet by making incense or soup. It was used in Tibetan medicine for the treatment of influenza, cold, wounds, fever, and skin diseases.

• anti-influenza  : Bioactivity evaluation of the essential oil revealed that it exhibited potent anti-influenza effect on viruses H3/N2
• anti-inflammatory effect by inhibiting the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages, but no anti-complementary activity.
• Cancer : The APEO demonstrated anti-hepatoma activity against SMMC-7721 hepatoma cell line with IC50 lower than 55 μg/mL. At the same time, nucleus shrinkage or broken were found in cells incubated with APEO through fluorescent microscope. In addition, pro-apoptosis and cell cycle arrest effects were confirmed by flow cytometry analysis.

References

• Giorgi, A.; Panseri, S.; Mattara, M.S.; Andreis, C.; Chiesa, L.M. Secondary metabolites and antioxidant capacities of Waldheimia glabra (Decne.) Regel from Nepal. J. Sci. Food Agric. 2013, 93, 1026–1034.
• Manzo, A.; Musso, L.; Panseri, S.; Iriti, M.; Dallavalle, S.; Catalano, E.; Scarì, G.; Giorgi, A. Screening of the chemical composition and bioactivity of Waldheimia glabra (Decne.) Regel essential oil. J. Sci. Food Agric. 2016, 96, 3195–3201.
• https://www.tandfonline.com/doi/abs/10.1080/14786419.2016.1233411?scroll=top&needAccess=true&journalCode=gnpl20