Prebiotics
Prebiotics are non-digestible food ingredients that stimulate the growth and/or activity of bacteria in the digestive system in ways claimed to be beneficial to health.As a functional food component, prebiotics, like probiotics, are conceptually intermediate between foods and drugs, and typically receive, depending on the jurisdiction, an intermediate level of regulatory scrutiny, in particular of the Health claims on food labels health claims made concerning them.
Typically, prebiotics are carbohydrates (such as oligosaccharides), but the definition may include non-carbohydrates. The most prevalent forms of prebiotics are nutritionally classed as soluble fiber. To some extent, many forms of dietary fiber exhibit some level of prebiotic effect.
Function
The prebiotic definition does not emphasize a specific bacterial group. Generally, however, it is assumed that a prebiotic should increase the number and/or activity of bifidobacteria and lactic acid bacteria. The importance of the bifidobacteria and the lactic acid bacteria (AKA lactobacillus or LABs) is that these groups of bacteria have several beneficial effects on the host, especially in terms of improving digestion (including enhancing mineral absorption<ref>Coxam V; Current data with inulin-type fructans and calcium, targeting bone health in adults. J Nutr. 2007; 137(11 Suppl): P-2527S</ref>) and the effectiveness and intrinsic strength of the immune system.<ref>Stephanie Seifert and Bernhard Watzl; Inulin and Oligofructose: Review of Experimental Data on Immune Modulation. J Nutr. 2007; 137: 2563S</ref> A product that stimulates bifidobacteria is considered a bifidogenic factor. Some prebiotics may thus also act as a bifidogenic factor and vice versa, but the two concepts are not identical.<ref>Food-Info.net Wageningen University</ref>
Sources
Traditional dietary sources of prebiotics include soybeans, inulin sources (such as Jerusalem artichoke, jicama, and Chicory root), raw oats, unrefined wheat, unrefined barley and yacon. Some of the oligosaccharides that naturally occur in breast milk are believed to play an important role in the development of a healthy immune system in infants.
It is becoming more common to properly distinguish between prebiotic substances and the food that contains them. References to almonds, honey and other foods (most commonly in promotional materials from growers of those foods) as "a prebiotic" are not accurate. No plant or food is a prebiotic: Wheat, honey and many other foods contain prebiotics to a greater or lesser extent, ranging from fairly large portions (chicory root, Jerusalem artichoke) to only trace quantities (thousands of other plant-based foods). Referring to a food as "a prebiotic" is no more accurate than calling a food "a vitamin."
Top 10 Foods Containing Prebiotics
| Food | Prebiotic Fiber Content by Weight |
|---|---|
| Raw Chicory Root | 64.6% |
| Raw Jerusalem Artichoke | 31.5% |
| Raw Dandelion Greens | 24.3% |
| Raw Garlic | 17.5% |
| Raw Leek | 11.7% |
| Raw Onion | 8.6% |
| Cooked Onion | 5% |
| Raw Asparagus | 5% |
| Raw Wheat bran | 5% |
| Whole Wheat flour, Cooked | 4.8% |
| Raw Banana | 1% |
While there is no broad consensus on an ideal daily serving of prebiotics, recommendations typically range from 4-8g for general digestive health support, to 15g or more for those with active digestive disorders. Given an average 6g serving, below are the amounts of prebiotic foods required to achieve a daily serving of prebiotic fiber:
| Food | Amount of food to achieve 6g serving of prebiotics |
|---|---|
| Raw Chicory Root | 9.3g (about 1/3 oz) |
| Raw Jerusalem Artichoke | 19g (about 3/4 oz) |
| Raw Dandelion Greens | 24.7g (just under 1 oz) |
| Raw Garlic | 34.3 g (about 1.2 oz) |
| Raw Leek | 51.3g (about 1.8 oz) |
| Raw Onion | 69.8g (about 2.5 oz) |
| Cooked Onion | 120g (about 1/4 lb) |
| Raw Asparagus | 120g (about 1/4 lb) |
| Raw Wheat Bran | 120g (about 1/4 lb) |
| Whole Wheat Flour, Cooked | 125g (about 1/4 lb) |
| Raw Banana | 600g (about 1.3 lb) |
Those wishing to ensure sufficient prebiotic intake should carefully consider the prebiotic content of their diet, as well as what caloric/nutritive load comes along with it: e.g. eating 1.3 pounds of bananas daily is likely to provide an excess of calories & sugars/carbohydrates to the diet. Prebiotic fiber supplements with minimal caloric/fat/sugar load are also available.
Prebiotic oligosaccharides are increasingly added to foods for their health benefits. Some oligosaccharides that are used in this manner are fructooligosaccharides (FOS), xylooligosaccharides (XOS), polydextrose and galactooligosaccharides (GOS). Some monosaccharides such as tagatose are also used sometimes as prebiotics.
In petfood also mannooligosaccharides are being used for prebiotic purposes.
Effects
Studies have demonstrated positive effects on calcium and other mineral absorption<ref>Katharina E. Scholz-Ahrens, Jürgen Schrezenmeir ; Inulin and Oligofructose and Mineral Metabolism: The Evidence from Animal Trials. J Nutr. 2007; 137: 2513S</ref>, immune system effectiveness<ref>Lomax AR, Calder PC. Prebiotics, immune function, infection and inflammation: a review of the evidence. Institute of Human Nutrition, School of Medicine, University of Southampton, Tremona Road, Southampton, UK</ref>, bowel pH, reduction of colorectal cancer risk<ref>Geier MS et al; Probiotics, prebiotics and synbiotics: a role in chemoprevention for colorectal cancer? Cancer Biol Ther. 2006; 5(10): P-1265-9</ref>, inflammatory bowel disorders (Crohn's Disease and Ulcerative Colitis) <ref>Hedin C et al; Evidence for the use of probiotics and prebiotics in inflammatory bowel disease: a review of clinical trials. Proc Nutr Soc. 2007; 66(3): P-307-15</ref> Hypertension (high blood pressure) <ref>Antihypertensive Properties of Plant-Based Prebiotics: Siok-Koon Yeo, Lay-Gaik Ooi, Ting-Jin Lim, and Min-Tze Liong* School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia</ref> and intestinal regularity. Template:Citation needed Recent human trials have reinforced the role of Prebiotics in preventing and possibly stopping early stage colon cancer.<ref>British Journal of Nutrition; September 2009, Volume 102, Issue 05, pp 663-671, “Fermentation products of inulin-type fructans reduce proliferation and induce apoptosis in human colon tumour cells of different stages of carcinogenesis” Authors: U. Munjal, M. Glei, B.L. Pool-Zobel, D. Scharlau</ref> It has been argued that many of these health effects emanate from increased production of short-chain fatty acids (SCFA) by the stimulated beneficial bacteria. Thus food supplements specifically enhancing the growth of SCFA producing intestinal bacteria (such as clostridium|clostridia and bacteroides species) are widely recognized to be beneficial.
While research does clearly demonstrate that prebiotics lead to increased production of these SCFA's<ref>Macfarlane S et al; Prebiotics in the gastrointestinal tract Aliment Pharmacol Ther. 2006; 24(5): P-701-14;</ref>, more research is required to establish a direct causal connection. It has been argued that prebiotics are beneficial to Crohn's Disease through production of SCFAs to nourish the colon walls, and beneficial to Ulcerative Colitis through reduction of Hydrogen Sulfide gas due to reduction of sulfate-reducing bacteria, which do not thrive in the slightly acidic environment SCFAs create.
The immediate addition of substantial quantities of prebiotics to the diet may result in a temporary increase in gas, bloating or bowel movement. It has been argued that chronically low consumption of prebiotic-containing foods in the typical Western diet may exaggerate this effect. Template:Citation needed
Human colonic bacteria substrates are relatively stable. Production of SCFA and fermentation quality are reduced during long-term diets of low fiber intake.<ref>23L El Oufir, B Flourié, S Bruley des Varannes, J L Barry, D Cloarec, F Bornet, and J P Galmiche Relations between transit time, fermentation products, and hydrogen consuming flora in healthy humans. Gut. 1996 June; 38(6): 870–877. PMCID: PMC1383195</ref> Until bacterial flora are gradually established to habilitate or restore intestinal tone, nutrient absorption will be impaired and colonic transit time temporarily increased with an immediate addition of higher prebiotic intake.<ref>24Givson, G. R., Willems, A., Reading, S., Collins, M. D. Fermentation of non-digestible oligosaccharides by human colonic bacteria. Symposium 2. Proceedings of the Nutrition Society (1996), 55, 899-912.</ref>
See also
References
External links
- Food-Info.net on prebiotics and bifidogenic factors
- International Scientific Association for Probiotics and Prebiotics
- http://www.raysahelian.com/prebiotic.html
- http://www.sciencedaily.com/releases/2008/06/080627163121.htm
- http://www.sciencedaily.com/releases/2008/04/080401200444.htm
- http://www.prebiotic.ca/prebiotic_fibre.html
- http://www.dailymail.co.uk/health/article-400681/The-facts-prebiotics.html
- http://www.innvista.com/health/nutrition/biotics/prebiot.htm
- http://books.google.com/books?id=y2rvBwMy6HgC&printsec=frontcover#PPA43,M1
- http://books.google.com/books?id=XgF_VEDw-REC&printsec=frontcover
