Cushing's Disease

Cushing's disease (also known as Cushing disease, tertiary or secondary hypercortisolism, tertiary or secondary hypercorticism, Itsenko-Cushing disease) is a cause of Cushing’s Syndrome characterised by increased secretion of adrenocorticotropic hormone (ACTH) from the anterior pituitary (secondary hypercortisolism). This is most often as a result of a pituitary adenoma (specifically pituitary basophilism) or due to excess production of hypothalamus CRH (Corticotropin releasing hormone) (tertiary hypercortisolism/hypercorticism) that stimulates the synthesis of cortisol by the adrenal glands.

Causes

The most common causes are the long-term use of oral steroid medications or a tumor of the pituitary gland. Certain herbal remedies may help to restore normal cortisol production. Check with your physician about the best course of treatment for you.

Natural Remedies

• Ginseng : Michael Murray, N.D. and Joseph Pizzorno, N.D., authors of “The Encyclopedia of Natural Medicine,” propose that excessive hormone release impairs the body’s ability to appropriately respond to stress. Both Panax ginseng and Siberian ginseng are regarded as adaptogens, which means that they enhance the body’s ability to cope with physical and mental stress. Specifically, the authors state that ginseng counteracts the negative effects of elevated serum cortisol levels. According to MayoClinic.com, ginseng is generally well tolerated and produces few side effects. However, people with a known sensitivity to plants in the Araliaceae family may experience an allergic reaction. In addition, ginseng may cause a drop in blood sugar and should not be used by diabetics. Ginseng may also interfere with other drugs, including blood thinners. Since certain compounds in ginseng may exert hormonal effects, this herb should not be used if there is a history of a hormone-related condition, such as breast or prostate cancer.
• Milk Thistle : Silibinin extracted from milk thistle seeds successfully treated Cushing's disease in cell cultures, animal models and human tumor tissue.

Medical Disclaimer

This information is not meant to be substituted for medical advice. Always consult a medical professional regarding any medical problems and before undertaking any treatment or dietary changes.