Difference between revisions of "Grape seed extract"

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==Special Precautions of Grape seed extract==
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See also :
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* [[Grapeseed Oil]]
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*[[Grapes]]
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[[Grapes]] (Vitis vinifera) have been heralded for their medicinal and nutritional value for thousands of years. Egyptians ate grapes at least 6,000 years ago, and several ancient Greek philosophers praised the healing power of grapes -- usually in the form of wine. European folk healers made an ointment from the sap of grapevines to treat skin and eye diseases. Grape leaves were used to stop bleeding, inflammation, and pain, such as the kind brought on by hemorrhoids. Unripe grapes were used to treat sore throats, and dried grapes (raisins) were used for constipation and thirst. Round, ripe, sweet grapes were used to treat a range of health problems including cancer, cholera, smallpox, nausea, eye infections, and skin, kidney, and liver diseases.But grapes -- or the chemicals within them, especially oligomeric proanthocyanidin complexes (OPCs) -- have been touted as powerful antioxidants. Some people believe they could help treat a number of conditions, from heart disease to cancer to aging skin, although scientific evidence is mostly lacking for those conditions. However, there is good evidence that grape seed extract can help treat chronic venous insufficiency and edema. A study of healthy volunteers found that taking grape seed extract did substantially increase levels of antioxidants in their blood. Antioxidants are substances that destroy free radicals -- harmful compounds in the body that damage DNA (genetic material) and even cause cell death. Free radicals are believed to contribute to aging, as well as the development of a number of health problems, including heart disease and cancer
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==Special Precautions of Grape seed extract (side effects)==
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*The National Center for Complementary and Alternative Medicine reports a variety of side effects associated with grape seed extract. You may experience gastrointestinal problems, such as indigestion and nausea, or possibly a headache or dizziness. Other side effects to watch for include an itchy scalp, hives and high blood pressure.
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*Do not use [[Grapeseed Oil]] or Grape seed extract if you're allergic to [[grapes]]. People who are allergic to cherries and strawberries also have a good chance of being sensitive to grapes, so consult your health care provider if you have any food allergy concerns. 
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* If you have a bleeding disorder or high blood pressure, talk to your doctor before you start using grape seed extract.
 +
*Interactions. If you take any medicines regularly, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), certain heart medicines, cancer treatments, and others.
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*Given the lack of evidence about its safety, grape seed extract is not recommended for children or for women who are pregnant or breastfeeding.
 +
 
 
==The benefits of Grape seed extract are==
 
==The benefits of Grape seed extract are==
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The therapeutic potential of grape seed extract (GSE) as anti-oxidant, anti-hypertensive and anti-inflammatory is so well established that this natural supplement is now being used in seven on-going clinical trials, only one of which is on cancer (of the breast). But the spotlight may soon shift to GSE's anti-cancer potential as recent landmark studies on human patients have just uncovered remarkable protective effects of GSE against three major cancers: squamous cell carcinoma and prostate and hematologic malignancies. Even more remarkable is that this breakthrough in the science of natural medicine was not due to the foresight of medical practitioners who designed the trials, but to the patients who took GSE, on their volition, as a nutritional supplement to support general health. The immune-boosting supplement has 50 times stronger antioxidant properties than vitamin C and 20 times stronger than vitamin E.
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Since ancient Greece, various parts of the grape have been used for medicinal purposes. Grape seed extract is purported to help treat the following health problems:
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*[[High Blood Pressure]] : In a 2009 study of subjects with metabolic syndrome, researchers found that four weeks of treatment with grape seed extract lowered both systolic and diastolic blood pressure. Metabolic syndrome is marked by a cluster of health problems (including excess belly fat, high blood pressure, high cholesterol, insulin resistance, and inflammation) known to raise your risk of heart disease and type 2 diabetes.
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*74% Risk Reduction of Skin Cancer (SCC): A recent study, just published in June 2011, was carried out in northern California on 830 participants to test the effects of general supplement use on the occurrence of squamous cell carcinoma (the second most common skin cancer). The supplements in use included vitamins A, C, D, E, multivitamins and GSE. Only the users of GSE experienced a significant reduction in risk (P = 0.031) of squamous cell carcinoma--by an astounding 74%. Multivitamin users experienced 29% reduced risk, but this was only borderline statistically significant.
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*high [[Cholesterol]]
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*atherosclerosis
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*62% Risk Reduction of Prostate Cancer: A much larger study conducted in Washington State tracked 35,239 male participants starting in the year 2000 in the VITamins and Lifestyle (VITAL) cohort. Participants, aged 50-76 years, answered detailed questionnaires about specialty supplement use for the 10 years prior to the start of the study. Prostate cancer risk was assessed after a median follow-up time of 6.1 years. The results showed GSE to be the stand-alone winner. Men, who used an individual grape seed extract supplement with "high average use" over 10 years, experienced a significant 62% risk reduction of prostate cancer compared to non-users, while average users of GSE supplements experienced a 41% risk reduction. None of the other supplements observed in this study (CoQ10, fish oil, garlic pills, ginkgo biloba, ginseng, glucosamine, chondroitin or saw palmetto) were seen to offer protection against prostate cancer. Note, however, that green tea was not one of the supplements considered. This study was published in May 2011.
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*poor circulation
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*[[Diabetes]]-Related Complications : In a 2009 study of 32 type 2 diabetes patients at high cardiovascular risk, participants took 600 mg of grape seed extract or a placebo every day for four weeks. Study results showed that grape seed extract significantly improved markers of inflammation and glycemia. The study's authors suggest that grape seed extract may have a therapeutic role in decreasing cardiovascular risk.
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*43% Risk Reduction of Hematologic Cancers : The same VITAL cohort as used for the prostate cancer study was also used to assess risk of hematologic cancers (involving blood, bone marrow or lymph nodes). The population was expanded to include women, for a total of 66,227 participants. Those who had ever used grape seed supplements saw a 43% risk reduction for hematologic cancers. This was only matched by those with a "high use" of garlic, who saw a 47% reduction of risk. No other supplements offered significant protection. This study was published in August 2011.
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*gastrointestinal disorders
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* [[anti-inflammatory]] : Grape seed extract contains polyphenols which have been shown in clinical studies to exhibit anti-inflammatory activity
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* In addition to the above cancers, GSE has already demonstrated cytotoxicity to breast cancer, colon cancer, glioblastoma, and NSC lung cancer cells in laboratory studies. But the three study results on human populations given above provide a dramatic leap forward for the science backing GSE as an anti-cancer supplement. It is astounding, then, that none of the studies received much media attention. That will likely require full-blown clinical trials, which will almost certainly be kicked-off as a result of these studies, but will take years to complete. Until then, the latest findings on GSE make a compelling case for its consideration in any program or supplement regimen meant to reduce cancer risk.
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*[[Constipation]]
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*[[Macular Degeneration]]
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* [[Cancer]] : In laboratory studies, scientists have demonstrated that grape seed can help fight free radicals (chemical by-products known to cause DNA damage associated with cancer). GSE has remarkable anti-cancer properties. At this time, laboratory tests show GSE can combat follwing cancers : leukemia, Skin, Breast, Colon, Lung, Stomach, Prostate-cancer.
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*[[Alzheimer's Disease]] : Grape seed extract may help delay the development of Alzheimer's disease, according to an animal study published in 2009. In tests on mice, scientists discovered that grape seed extract eased inflammation and prevented the accumulation of substances known to form the brain plaques associated with Alzheimer's disease.
 
[[Category:Treatments]]
 
[[Category:Treatments]]
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[[Category:X]]
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[[Category:fruit & vegetables]]
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[[Category:home remedies]]
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[[Category:Food Therapy]]
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[[Category:Anti-angiogenic]]

Latest revision as of 10:01, 7 November 2021

See also :

Grapes (Vitis vinifera) have been heralded for their medicinal and nutritional value for thousands of years. Egyptians ate grapes at least 6,000 years ago, and several ancient Greek philosophers praised the healing power of grapes -- usually in the form of wine. European folk healers made an ointment from the sap of grapevines to treat skin and eye diseases. Grape leaves were used to stop bleeding, inflammation, and pain, such as the kind brought on by hemorrhoids. Unripe grapes were used to treat sore throats, and dried grapes (raisins) were used for constipation and thirst. Round, ripe, sweet grapes were used to treat a range of health problems including cancer, cholera, smallpox, nausea, eye infections, and skin, kidney, and liver diseases.But grapes -- or the chemicals within them, especially oligomeric proanthocyanidin complexes (OPCs) -- have been touted as powerful antioxidants. Some people believe they could help treat a number of conditions, from heart disease to cancer to aging skin, although scientific evidence is mostly lacking for those conditions. However, there is good evidence that grape seed extract can help treat chronic venous insufficiency and edema. A study of healthy volunteers found that taking grape seed extract did substantially increase levels of antioxidants in their blood. Antioxidants are substances that destroy free radicals -- harmful compounds in the body that damage DNA (genetic material) and even cause cell death. Free radicals are believed to contribute to aging, as well as the development of a number of health problems, including heart disease and cancer

Special Precautions of Grape seed extract (side effects)

  • The National Center for Complementary and Alternative Medicine reports a variety of side effects associated with grape seed extract. You may experience gastrointestinal problems, such as indigestion and nausea, or possibly a headache or dizziness. Other side effects to watch for include an itchy scalp, hives and high blood pressure.
  • Do not use Grapeseed Oil or Grape seed extract if you're allergic to grapes. People who are allergic to cherries and strawberries also have a good chance of being sensitive to grapes, so consult your health care provider if you have any food allergy concerns.
  • If you have a bleeding disorder or high blood pressure, talk to your doctor before you start using grape seed extract.
  • Interactions. If you take any medicines regularly, talk to your doctor before you start using grape seed extract. It could interact with drugs like blood thinners, NSAID painkillers (like aspirin, Advil, and Aleve), certain heart medicines, cancer treatments, and others.
  • Given the lack of evidence about its safety, grape seed extract is not recommended for children or for women who are pregnant or breastfeeding.

The benefits of Grape seed extract are

Since ancient Greece, various parts of the grape have been used for medicinal purposes. Grape seed extract is purported to help treat the following health problems:

  • High Blood Pressure : In a 2009 study of subjects with metabolic syndrome, researchers found that four weeks of treatment with grape seed extract lowered both systolic and diastolic blood pressure. Metabolic syndrome is marked by a cluster of health problems (including excess belly fat, high blood pressure, high cholesterol, insulin resistance, and inflammation) known to raise your risk of heart disease and type 2 diabetes.
  • high Cholesterol
  • atherosclerosis
  • poor circulation
  • Diabetes-Related Complications : In a 2009 study of 32 type 2 diabetes patients at high cardiovascular risk, participants took 600 mg of grape seed extract or a placebo every day for four weeks. Study results showed that grape seed extract significantly improved markers of inflammation and glycemia. The study's authors suggest that grape seed extract may have a therapeutic role in decreasing cardiovascular risk.
  • gastrointestinal disorders
  • anti-inflammatory : Grape seed extract contains polyphenols which have been shown in clinical studies to exhibit anti-inflammatory activity
  • Constipation
  • Macular Degeneration
  • Cancer : In laboratory studies, scientists have demonstrated that grape seed can help fight free radicals (chemical by-products known to cause DNA damage associated with cancer). GSE has remarkable anti-cancer properties. At this time, laboratory tests show GSE can combat follwing cancers : leukemia, Skin, Breast, Colon, Lung, Stomach, Prostate-cancer.
  • Alzheimer's Disease : Grape seed extract may help delay the development of Alzheimer's disease, according to an animal study published in 2009. In tests on mice, scientists discovered that grape seed extract eased inflammation and prevented the accumulation of substances known to form the brain plaques associated with Alzheimer's disease.
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