Difference between revisions of "Lycopene"

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*Lycopene for Healthy Skin : Lycopene can be used as a sunscreen and antioxidant in one. Once in the body, lycopene deters skin aging by destroying free radicals and protects the skin from the inside against damage caused by the UV rays of the sun. Lycopene supplements and lycopene skin care products like lycopene lotion with relatively efficient SPF levels are crowding the market. The lycopene content of these products may come from natural sources or they may have been synthesized artificially. But if you want it the natural way and not from a tube, there will always be the ketchup in the cupboard.
 
*Lycopene for Healthy Skin : Lycopene can be used as a sunscreen and antioxidant in one. Once in the body, lycopene deters skin aging by destroying free radicals and protects the skin from the inside against damage caused by the UV rays of the sun. Lycopene supplements and lycopene skin care products like lycopene lotion with relatively efficient SPF levels are crowding the market. The lycopene content of these products may come from natural sources or they may have been synthesized artificially. But if you want it the natural way and not from a tube, there will always be the ketchup in the cupboard.
 
* eyesight : Lycopene is a high-powered antioxidant that comes from tomatoes. Along with lutien and zeaxanthin this natural supplement can also protect your cells and tissues from free radical damage. Scientific evidence has demonstrated the protective effects of dietary tomatoes on the oxidative stress in the retinal pigment epithelium.
 
* eyesight : Lycopene is a high-powered antioxidant that comes from tomatoes. Along with lutien and zeaxanthin this natural supplement can also protect your cells and tissues from free radical damage. Scientific evidence has demonstrated the protective effects of dietary tomatoes on the oxidative stress in the retinal pigment epithelium.
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==Dietary sources==
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{| class="wikitable" table style="border:1px #000000;" cellspacing="0" align="left" style="margin-left: 1em"
 +
|-
 +
!colspan="2"|Dietary sources of lycopene<ref>Rao and Rao (2007) pp. 209&ndash;210</ref>
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|-
 +
! width="100" | Source
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! width="150" | μg/g wet weight
 +
|-
 +
| [[Gac]]
 +
| 2,000&ndash;2,300
 +
|-
 +
| Raw [[tomato]]
 +
| 8.8&ndash;42
 +
|-
 +
| Tomato juice
 +
| 86&ndash;100
 +
|-
 +
| Tomato sauce
 +
| 63&ndash;131
 +
|-
 +
| Tomato [[ketchup]]
 +
| 124
 +
|-
 +
| [[Watermelon]]
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| 23&ndash;72
 +
|-
 +
| [[Pink grapefruit]]
 +
| 3.6&ndash;34
 +
|-
 +
| Pink [[guava]]
 +
| 54
 +
|-
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| [[Papaya]]
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| 20&ndash;53
 +
|-
 +
| [[Rosehip]] puree
 +
| 7.8
 +
|-
 +
| [[Apricot]]
 +
| < 0.1
 +
|}
 +
[[Fruit]]s and [[vegetable]]s that are high in lycopene include [[gac]], tomatoes, [[watermelon]], pink [[grapefruit]], pink [[guava]], [[papaya]], [[seabuckthorn]], [[wolfberry]] (goji, a berry relative of tomato), and [[rosehip]]. Although [[gac]] (''Momordica cochinchinensis'' Spreng) has the highest content of lycopene of any known fruit or vegetable, up to 70 times more than tomatoes for example,<ref>USDA study on Cartenoid content of gac fruit</ref> due to gac's rarity outside its native region of southeast [[Asia]], tomatoes and tomato-based sauces, juices, and ketchup account for more than 85% of the dietary intake of lycopene for most people.<ref>Rao (2007) p.</ref> The lycopene content of tomatoes depends on species and increases as the fruit ripens.<ref>Khan ''et al.'' (2008) p. 495</ref>
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 +
Unlike other fruits and vegetables, where nutritional content such as [[vitamin C]] is diminished upon cooking, [[food processing|processing]] of tomatoes increases the concentration of [[Bioavailability|bioavailable]] lycopene.  Lycopene in tomato paste is four times more bioavailable than in fresh tomatoes.  For this reason, tomato sauce is a preferable source as opposed to raw tomatoes.
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 +
While most green leafy vegetables and other sources of lycopene are low in fats and oils, lycopene is insoluble in water and is tightly bound to vegetable fiber.  Processed tomato products such as pasteurized tomato juice, soup, sauce, and ketchup contain the highest concentrations of bioavailable lycopene from tomato-based sources.
 +
 +
Cooking and crushing tomatoes (as in the [[canning]] process) and serving in oil-rich dishes (such as [[spaghetti]] sauce or [[pizza]]) greatly increases assimilation from the digestive tract into the bloodstream. Lycopene is fat-soluble, so the oil is said to help absorption. [[Gac]] is a notable exception, containing high concentrations of lycopene and also saturated and unsaturated fatty acids.<ref name="Ishida2004">{{Cite journal|author=Ishida BK, Turner C, Chapman MH, McKeon TA |title=Fatty acid and carotenoid composition of gac (Momordica cochinchinensis Spreng) fruit |journal=[[Journal of Agricultural and Food Chemistry]] |volume=52 |issue=2 |pages=274–9 |year=2004 |month=January |pmid=14733508 |doi=10.1021/jf030616i |url=}}</ref>
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Lycopene may be obtained from vegetables and fruits such as the tomato, but another source of lycopene is the fungus ''[[Blakeslea trispora]]''. [[Gac]] is a promising commercial source of lycopene for the purposes of extraction and purification.
 +
{{Clear}}
 +
 +
The cis-lycopene from some varieties of tomato is more bioavailable.<ref>http://www.medicalnewstoday.com/articles/64157.php</ref>
 +
 +
Note that there are some resources which make the mistaken assumption that all red fruits contain lycopene, when in fact many are [[pigment]]ed by other chemicals.  An example is the [[blood orange]], which is colored by [[anthocyanin]], while other red colored oranges, such as the [[Cara cara navel]], and other citrus fruit, such as [[pink grapefruit]], are colored by lycopene. 
 +
 +
In addition, some foods which do not appear red also contain lycopene, e.g., [[asparagus]], which contains about 30μg of lycopene per 100 gram serving<ref>{{cite web | title = Nutrition Facts Comparison Tool, Asparagus | url = http://www.healthaliciousness.com/nutritionfacts/nutrition-comparison.php?o=11012&t=11012&h=11012&s=100&e=90.00&r=60.00| accessdate = December 17, 2011}}</ref> and dried parsley and basil, which contain about 3.5-7 μg of lycopene per gram<ref>{{cite web | title = Nutrition Facts Comparison Tool, Spices Parsley, Basil | url =
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http://www.healthaliciousness.com/nutritionfacts/nutrition-comparison.php?o=2029&t=2029&h=2003&s=100&e=1.60&r=2.10 | accessdate = December 17, 2011 }}</ref>
  
 
[[Category:Treatments]]
 
[[Category:Treatments]]
 
[[Category:X]]
 
[[Category:X]]

Revision as of 12:22, 3 April 2012

Special Precautions of Lycopene

Anything taken in excessive dosage can have harmful effects to the body. Though lycopene is a non-toxic substance commonly found in the usual diet, excess in carotenoid intake may produce colorful side-effects – in the literal sense. Reports of excessive lycopene intake include the case of a woman who experienced skin discoloration called lycopenodermia after excessive and prolonged consumption of tomato products and tomato juice. Her blood had high levels of lycopene and her liver and skin had a yellow to orange color. The woman was advised to have a lycopene-free diet and after three weeks her skin regained its normal color.

The benefits of Lycopene are

A collaborative study conducted by Newcastle University, the University of Manchester and Salford Royal NHS Foundation Trust, revealed that consumption of foods containing Lycopene reduces the reddening of the skin after long hours of exposure to the sun’s ultraviolet (UV) rays. Tomatoes are the richest known sources of lycopene and heat-treated tomato paste has more lycopene content than fresh raw tomatoes. A small serving of tomato paste contains approximately 16 milligrams of lycopene. Skin reddening brought about by extended exposure to UV rays is caused by the damage to mitochondrial DNA. Sufficient servings of tomato paste on a daily basis protect mitochondrial DNA from damage, thereby reducing skin reddening and keeping the skin healthy. This study was published in the British Journal of Dermatology.

The study on the dermatological benefits of lycopene supports previous findings regarding its protective properties against UV rays and tissue damage. However, the research has only produced preliminary evidence and further research is still needed. Lycopene is also a known antioxidant and the substance has also shown medical evidence for lowering the risk of developing prostate, skin and heart diseases. It is also essential in keeping the bones healthy. While lycopene has been known to be derived naturally from tomatoes, it can also be produced synthetically. As an additional treat, lycopene is also being used in cosmetic and beauty products, and in food supplements.

The lycopene study consisted of twenty healthy female participants with an average age of 33. Their skin type was identified as phototype I/II. They were asked randomly to take 55 grams of olive oil or tomato paste in olive oil for a period of 12 weeks. Skin samples from the 17 women who completed the study showed that lycopene had improved the skin’s resistance to UV rays. The researchers said that the benefits of lycopene can also be acquired by eating foods containing processed tomatoes in equivalent dosage.

Understanding Lycopene

Lycopene is a bright red carotenoid and carotene pigment found in red fruits and vegetables especially tomatoes, except for cherries and strawberries. Other known sources are red carrots, papayas, watermelons. Lycopene in plants, and in other organisms that require the process of photosynthesis in making food, serve as an important substance in biosynthesizing carotenoids to give the plant its pigmentation. In humans, lycopene is not an essential nutrient but it is commonly found in the usual diet. The richest source of lycopene is processed and heat-treated tomato products like tomato paste and tomato ketchup. Preliminary evidence from several studies regarding lycopene’s antioxidant properties has made it one of the candidates as a potential agent in the prevention of cancer.

Sources of Lycopene

Lycopene in food supplements and beauty products is usually extracted from tomatoes but the substance can also be synthesized. Amongst the richest natural source of lycopene are pink guava, wolfberry, seabuckthorn, red bell pepper, gac, papaya and of course, tomatoes. Raw tomatoes contain 9 micrograms of lycopene per 42 grams or weight. Some species of tomatoes can have higher lycopene content than others and it rises as the fruit begins to ripen. Gac is known to have the highest content of lycopene with up to 70 times more than tomatoes, but gac is rarely found outside the regions of Southeast Asia.

Antioxidant Properties of Lycopene : Singlet oxygen is produced during a person’s exposure to UV rays and it is the primary cause of skin aging. Carotenoid quenchers are needed to counteract the adverse effects of singlet oxygen to the body. In studies, lycopene has 125 times more the quenching power than glutathione and 100 times more than vitamin. This makes it one of the most potent antioxidants and also one of the most effective substances against skin aging from a natural source.

Health Benefits of Lycopene

Lycopene is continuously being studied for its efficacy in the prevention of several types of cancer. Studies have shown significant evidence of lycopene’s protective properties against lung cancer, prostate cancer and cancer of the stomach. But results and findings remain preliminary and inconclusive, and further research is required to really determine the efficacy of lycopene as an anti-cancer agent.

  • Asthma : Though no concrete evidence has been established regarding this matter, lycopene had shown indication from scientific studies of being potent in preventing asthma caused by exercise and heightened physical exertion. This is rooted mainly on lycopene’s antioxidant properties.
  • Cancer Prevention : Studies done in animals to determine the relationship of developing cancer and regular consumption of lycopene from tomatoes showed indications of reduced risk. But like any other studies regarding lycopene, results are still inconclusive and preliminary. Nevertheless, population and epidemiologic studies on the dietary habits and lifestyle of large populations showed lower risk of developing cancer for people with sufficient fruits and vegetable consumption and adequate exercise than the portion of the population with a sedentary lifestyle. It’s not clear whether lycopene is contributory to the effect, but studies are continuously investigating the matter. Despite all the uncertainties, getting sufficient dosage of lycopene from tomatoes and processed tomato products will not harm you either.
  • Lycopene for Healthy Skin : Lycopene can be used as a sunscreen and antioxidant in one. Once in the body, lycopene deters skin aging by destroying free radicals and protects the skin from the inside against damage caused by the UV rays of the sun. Lycopene supplements and lycopene skin care products like lycopene lotion with relatively efficient SPF levels are crowding the market. The lycopene content of these products may come from natural sources or they may have been synthesized artificially. But if you want it the natural way and not from a tube, there will always be the ketchup in the cupboard.
  • eyesight : Lycopene is a high-powered antioxidant that comes from tomatoes. Along with lutien and zeaxanthin this natural supplement can also protect your cells and tissues from free radical damage. Scientific evidence has demonstrated the protective effects of dietary tomatoes on the oxidative stress in the retinal pigment epithelium.

Dietary sources

Dietary sources of lycopene<ref>Rao and Rao (2007) pp. 209–210</ref>
Source μg/g wet weight
Gac 2,000–2,300
Raw tomato 8.8–42
Tomato juice 86–100
Tomato sauce 63–131
Tomato ketchup 124
Watermelon 23–72
Pink grapefruit 3.6–34
Pink guava 54
Papaya 20–53
Rosehip puree 7.8
Apricot < 0.1

Fruits and vegetables that are high in lycopene include gac, tomatoes, watermelon, pink grapefruit, pink guava, papaya, seabuckthorn, wolfberry (goji, a berry relative of tomato), and rosehip. Although gac (Momordica cochinchinensis Spreng) has the highest content of lycopene of any known fruit or vegetable, up to 70 times more than tomatoes for example,<ref>USDA study on Cartenoid content of gac fruit</ref> due to gac's rarity outside its native region of southeast Asia, tomatoes and tomato-based sauces, juices, and ketchup account for more than 85% of the dietary intake of lycopene for most people.<ref>Rao (2007) p.</ref> The lycopene content of tomatoes depends on species and increases as the fruit ripens.<ref>Khan et al. (2008) p. 495</ref>

Unlike other fruits and vegetables, where nutritional content such as vitamin C is diminished upon cooking, processing of tomatoes increases the concentration of bioavailable lycopene. Lycopene in tomato paste is four times more bioavailable than in fresh tomatoes. For this reason, tomato sauce is a preferable source as opposed to raw tomatoes.

While most green leafy vegetables and other sources of lycopene are low in fats and oils, lycopene is insoluble in water and is tightly bound to vegetable fiber. Processed tomato products such as pasteurized tomato juice, soup, sauce, and ketchup contain the highest concentrations of bioavailable lycopene from tomato-based sources.

Cooking and crushing tomatoes (as in the canning process) and serving in oil-rich dishes (such as spaghetti sauce or pizza) greatly increases assimilation from the digestive tract into the bloodstream. Lycopene is fat-soluble, so the oil is said to help absorption. Gac is a notable exception, containing high concentrations of lycopene and also saturated and unsaturated fatty acids.<ref name="Ishida2004">Template:Cite journal</ref>

Lycopene may be obtained from vegetables and fruits such as the tomato, but another source of lycopene is the fungus Blakeslea trispora. Gac is a promising commercial source of lycopene for the purposes of extraction and purification. Template:Clear

The cis-lycopene from some varieties of tomato is more bioavailable.<ref>http://www.medicalnewstoday.com/articles/64157.php</ref>

Note that there are some resources which make the mistaken assumption that all red fruits contain lycopene, when in fact many are pigmented by other chemicals. An example is the blood orange, which is colored by anthocyanin, while other red colored oranges, such as the Cara cara navel, and other citrus fruit, such as pink grapefruit, are colored by lycopene.

In addition, some foods which do not appear red also contain lycopene, e.g., asparagus, which contains about 30μg of lycopene per 100 gram serving<ref>Template:Cite web</ref> and dried parsley and basil, which contain about 3.5-7 μg of lycopene per gram<ref>Template:Cite web</ref>