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Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules (lumps that occur as a result of a process in which damaged tissue is regenerated),leading to loss of liver function. Cirrhosis is most commonly caused by alcoholism, [[hepatitis ]] B and C, and fatty liver disease, but has many other possible causes. Some cases are idiopathic, i.e., of unknown cause.