A 1994 study conducted in London by King's College revealed that Black Seed has properties that inhibit certain enzymes, which also inhibit the production of certain prostaglandins. This is more proof that the rich and complex combination of elements found in Black Seed work together for a total effect.
==Special Precautions of Black Seed==
*Black seed, when used in small quantities, such as a flavoring for foods, appears to be safe for most people. There isn't enough information to know if larger, medicinal quantities are safe. * Contact Dermatitis : Topical application of Nigella sativa may induce a side effect called contact dermatitis. After handling or applying Nigella sativa, you may develop red, irritated patches of skin across the site of treatment. The skin may also become dry or begin to flake or itch. Seek prompt medical care if you experience a severe skin reaction, such as oozing or painful blisters, after using this supplement. Black seed can cause allergic rashes when applied to the skin.* Kidney or Liver Damage : Oil extracted from Nigella sativa seeds may cause kidney or liver damage when used in high doses. These severe side effects of treatment were observed in rats given 2 grams per kilogram or more of Nigella sativa oil, according to MSKCC. Additional human research studies are necessary to further evaluate the effect Nigella sativa may have on the kidneys or liver; however, if you experience symptoms of kidney or liver damage, such as back or abdominal pain, urination changes, jaundice, fatigue or itchy skin, seek prompt care from your medical provider.
*Pregnancy and breast-feeding: Black seed seems to be safe in food amounts during pregnancy. But taking larger medicinal amounts is UNSAFE. Black seed can slow down or stop the uterus from contracting.
*Not much is known about the safety of using black seed during breast-feeding. Stay on the safe side and avoid use.