* An infusion of the roots has also been used to treat piles, though the report does not specify if it is used internally or externally.
* It stimulates the secretion of bile and bilirubin and may be helpful in correcting high tyramine levels in people with liver cirrhosis.
* Native Americans used Xanthorhiza simplicissima medicinally to treat ulcerated stomachs, colds, jaundice, piles, sore mouth, sore throat, cancer, and cramps, and as a blood tonic
==References==
* Foster. S. & Duke. J. A. A Field Guide to Medicinal Plants. Eastern and Central N. America. Houghton Mifflin Co. 1990 ISBN 0395467225