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Coenzyme Q10

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See also : [[Ubiquinol]]<br>Other Names: Co Q10, Co Q-10, Coenzima Q-10, Co-Enzyme 10, Coenzyme Q 10, Coenzyme Q10, Co-Enzyme Q10, Co-Enzyme Q-10, Co-Q 10, CoQ10, Co -Q10, UbiquinoneCoQ-10, Vitamin QUbidcarenone, Ubidécarénone, Ubiquinone-10.<br>CoQ-10 is a nutrient produced by the “energy factories” in your cells called mitochondria. Taking Coenzyme Q10 is a CoQnaturally-10 supplement boosts occuring compound found in every cell in the way your cells produce and use energy. It also helps your body burn fat ... improves cholesterol ratios ... boosts your physical energy levels ... and improves thyroid and pancreas functions.*cholesterol-lowering drugs -- actually deplete your body’s natural CoQ-10. Statins block production of cholesterol in the liverCoenzyme Q10's alternate name, where CoQ-10 is also manufactured. Without sufficient CoQ-10ubiquinone, statins can cause liver damage ... irregular heartbeat ... muscle weakness ... leg cramps ... heart attack and stroke (comes from the two potentially fatal conditions that statins are supposed to prevent).*Other medications also can limit your body’s production of CoQ-10word ubiquitous, including: Diabetes drugs ... antidepressants ... female hormone replacement therapy ... and blood pressure meds. If you take any of these, you definitely need to supplement with CoQ-10.*When shopping, labels may read “CoQ-10” or “Coenzyme Q-10”, but the more active form will be labeled “QH” or “ubiquinolwhich means "found everywhere.” This The mineral [[selenium]] is a stronger form of CoQ-10, though purchasing that version isn’t essential, especially if price is an issue. Take 100 mg two or three times twice per day, because your for the body can’t metabolize higher doses's natural production of Coenzyme Q10.
==Special Precautions of Coenzyme Q10==
* CoQ10 encourages blood clotting (a big no-no if you’re taking warfarin and other anti-coagulants), and can lower blood sugar and blood pressure to potentially dangerous levels.
* It may also interfere with chemotherapy treatment.
*CoQ10 and Statin Drugs : Some research suggests that statin drugs, or HMG-CoA reductase inhibitors, a class of drugs used to lower cholesterol, may interfere with the body's production of CoQ10. However, research on the use of CoQ10 supplements in people taking statins is still inconclusive, and it is not routinely recommended in combination with statin therapy.
* High blood pressure or low blood pressure: Coenzyme Q-10 might lower blood pressure. It can increase the effects of medications used to lower blood pressure. Discuss your use of coenzyme Q-10 with your healthcare provider if you have blood pressure problems.
*Surgery: Coenzyme Q-10 might interfere with blood pressure control during and after surgery. Stop using coenzyme Q-10 at least two weeks before a scheduled surgery.
* Coenzyme Q10 can potentially interfere with coumadin (Warfarin) and other blood-thinning medications.
==The benefits and uses of Coenzyme Q10 are==Coenzyme Q 10 is normally associated with anti-ageing skin care products. It is an oil-soluble substance which demonstrates similar properties with vitamins. Coenzyme Q 10 naturally occurs in eukaryotic cells and is an important element of the electron transport chain.The compound has been subjected to more than 5,000 clinical studies and its role in fighting the adverse effect of oxidative stress. As a person grows older, the body’s production of coenzyme Q 10 decreases. This makes the body more susceptible to disease like cancer and cardiovascular diseases. Coenzyme Q Taking a CoQ-10 can potentially help in strengthening supplement boosts the immune system way your cells produce and is use energy. It also effective as a secondary treatment against cancer. Numerous studies have established helps your body burn fat, improves cholesterol ratios, boosts your physical energy levels and improves thyroid and gathered significant evidence to support the health benefits of coenzyme Q 10pancreas functions. This makes CoQ10 is fat-soluble. Take it one with a bit of the most significant and popular food supplements in the marketolive oil or fish oil. Though normally used as Or have your CoQ10 with a topical treatmentmeal that includes fish, the benefits of coenzyme Q 10 can be better obtained through oral consumption. I recommend the brand Jarrow Formulasdairy, which is oil basedeggs or meat. This The powdered form of CoQ10 is important for a CoQ10 supplementmore difficult to absorb. Try either gel caps or tablets and take them with some kind of fat.  * Coenzyme Q10 Q-10 deficiency. This is a naturally-occuring compound found in every cell in the bodyvery rare condition. Coenzyme Q10's alternate nameThe symptoms include weakness, ubiquinonefatigue, comes from the word ubiquitous, which means "found everywhereand seizures. The mineral [[selenium]] is essential for the body's natural production of Coenzyme Q10." CoQ10 plays a key role in producing * Inherited or acquired disorders that limit energy production in the mitochondria, the part cells of a cell responsible for the production of energy body (mitochondrial disorders). Improvement in symptoms is slow. Some people have to take coenzyme Q-10 for six months to get the form of ATPmost benefitCoenzyme Q10 is used for :*Heart failure :People with Congestive heart failure have been found to have lower levels of CoQ10 in heart muscle cells(CHF). Double-blind research suggests There is no evidence that CoQ10 may reduce symptoms related to taking coenzyme Q-10 alone can help heart failure, such as shortness of breath, difficulty sleeping, and swelling. CoQ10 But there is thought to increase energy production some evidence (though controversial) that it might be helpful when taken in the combination with other heart muscle, increasing failure medications and treatments.*Decreasing the strength risk of the pumping action. Recent human studiesadditional heart problems in people who have had a recent heart attack (myocardial infarction, however, haven't supported thisMI).In When started within 72 hours of MI and taken for one studyyear, 641 people with congestive coenzyme Q-10 appears to significantly lower the risk of heart failure were randomized -related events including non-fatal MI.*Preventing blood vessel complications caused by heart bypass surgery. There is some evidence that taking coenzyme Q-10 by mouth for a week before surgery might help to receive either CoQ10 reduce blood vessel damage. But not all research agrees with this finding.*High blood pressure (2 mg per kg body weighthypertension) . Taking coenzyme Q-10 by itself or a placebo plus standard treatmentalong with other medications for treating high blood pressure seems to help lower blood pressure even more. People who took *Preventing migraine headache. Taking coenzyme Q-10 by mouth seems to help prevent migraine headaches. Studies show it can decrease the CoQ10 had a significant reduction in symptom severity frequency of headaches by about 30% and fewer hospitalizations.In another study, 32 patients the number of days with endheadache-stage heart failure awaiting heart transplantation received either 60 mg related nausea by about 45% in adults. Taking coenzyme Q-10 also appears to reduce migraine frequency in children who have low levels of CoQ10 or a placebo for coenzyme Q-10. It can take up to 3 months. Patients who took the CoQ10 experienced a for significant improvement in functional status, clinical symptoms, and quality of lifebenefit. Unfortunately, however there were no changes coenzyme Q-10 doesn’t seem to be effective in echocardiogram (heart ultrasound) or in objective markerstreating migraines, once they have developed.A study randomized 55 patients *Parkinson’s disease. Some research shows that taking coenzyme Q-10 supplements might slow decline in people with congestive heart failure to receive either 200 mg per day of CoQ10 or early Parkinson’s disease. But taking a placebo coenzyme Q-10 supplement in addition people with mid-stage Parkinson’s disease does not seem to standard treatmentimprove symptoms. Although serum levels *Improving the immune system of CoQ10 increased in patients receiving CoQ10, CoQ10 didn't affect ejection fraction, peak oxygen consumptionpeople with HIV/AIDS.*Muscular dystrophy, or exercise durationan inherited disorder involving muscle wasting.A longerTaking coenzyme Q-term study investigated the use of 100 mg of CoQ10 or a placebo in addition 10 by mouth seems to standard treatment improve physical performance in 79 some patients with stable chronic congestive muscular dystrophy.* strengthening the immune system*Heart failure :People with heart failure. The results indicated that CoQ10 only slightly improved maximal exercise capacity and quality have been found to have lower levels of life compared with the placeboCoQ10 in heart muscle cells.
*Cardiomyopathy :Several small trials have found CoQ10 may be helpful for certain types of cardiomyopathy.
*Parkinson's disease : Lower levels of CoQ10 have also been observed in people with Parkinson's disease. Preliminary research has found that increasing CoQ10 may increase levels of the neurotransmitter dopamine, which is thought to be lowered in people with Parkinson's disease. It has also been suggested that CoQ10 might protect brain cells from damage by free radicals.A small, randomized controlled trial examined the use of 360 mg CoQ10 or a placebo in 28 treated and stable Parkinson's disease patients. After 4 weeks, CoQ10 provided a mild but significant significant mild improvement in early Parkinson's symptoms and significantly improved performance in visual function.A larger 16 month trial funded by the National Institutes of Health explored the use of CoQ10 (300, 600 or 1200 mg/day) or a placebo in 80 patients with early stage Parkinson's disease. The results suggested that CoQ10, especially at the 1200 mg per day dose, had a significant reduction in disability compared to those who took a placebo.
* Cancer : In a study conducted to evaluate the health benefits of coenzyme Q 10, researchers observed that cancer patients had lower levels of the compound than healthier individuals.
*Heart Attack Prevention and Recovery
*Weight loss
*eliminates depression and anxiety
*Huntington’s disease (a rare genetic neurological disorder). Ubiquinol, an altered form of coenzyme Q-10, has been granted “Orphan Drug Status” by the Federal Food and Drug Administration (FDA). This gives the maker of Ubiquinol some financial incentives to study its effectiveness for Huntington’s, a condition that is so rare (affecting less than 200,000 individuals) that pharmaceutical companies might not otherwise invest in developing a drug for it. However, taking coenzyme Q-10 by mouth in doses of 600 mg per day or less doesn’t seem to be effective for slowing the progression of Huntington’s disease.
== Food sources ==
Many {| class="wikitable"|+ CoQ<sub>10</sub> levels in selected foods contain CoQ10, including: ! Food !! Coenzyme Q<sub>10</sub> concentration [mg/kg]|-!Beef|-|heart|| 113|-|liver||39–50|-|muscle||26–40|-!Pork|-|heart ||11.8–128.2|-|liver ||22.7–54.0|-|muscle ||13.8–45.0|-!Chicken|-|heart ||116.2–132.2|-!Fish|-|sardine ||5–64|-|mackerel|-|red meat, flesh ||43–67|-|white flesh ||11–16|-|salmon, fresh sardines, ||4–8|-|tuna, mackerel, soybeans, ||5|-!Oils|-|soybean oil, ||54–280|-|olive ||4–160|-|grapeseed ||64–73|-|sunflower ||4–15|-|rice bran ||/|-|coconut |||-!Nuts|-|peanuts ||27|-|walnuts ||19|-|sesame oilseeds ||18–23|-|pistachio nuts ||20|-|hazelnuts ||17|-|almond ||5–14|-!Vegetables|-|parsley ||8–26|-|broccoli ||6–9|-|cauliflower ||2–7|-|spinach ||up to 10|-|grape ||6–7|-|Chinese cabbage ||2–5|-!Fruit|-|avocado ||10|-|blackcurrant ||3|-|strawberry ||1|-|orange ||1–2|-|grapefruit ||1|-|apple ||1|} Meat and fish are the richest source of dietary CoQ<sub>10</sub> and levels over 50&nbsp;mg/kg can be found in beef, peanutspork and chicken heart, walnutsand chicken liver. Dairy products are much poorer sources of CoQ<sub>10</sub> compared to animal tissues. Vegetable oils are also quite rich in CoQ<sub>10</sub>. Within vegetables, broccoliparsley, spinachand perilla are the richest CoQ<sub>10</sub> sources, but significant differences in their CoQ<sub>10</sub> levels can be found in the literature. [[Broccoli]], grape, and whole grainscauliflower are modest sources of CoQ<sub>10</sub>. To get Most fruit and berries represent a poor to very poor source of CoQ<sub>10</sub>, with the biggest benefitexception of [[avocado]], avoid overwith a relatively high CoQ<sub>10</sub> content.* The mineral [[selenium]] is essential for the body's natural production of Coenzyme Q10.*cholesterol-cooking meat sources lowering drugs -- actually deplete your body’s natural CoQ-10. Statins block production of CoQ10cholesterol in the liver, where CoQ-10 is also manufactured. Without sufficient CoQ-10, statins can cause liver damage ... irregular heartbeat ... muscle weakness ... leg cramps ... heart attack and eat stroke (the nontwo potentially fatal conditions that statins are supposed to prevent).*Other medications also can limit your body’s production of CoQ-meat sources raw10, including: Diabetes drugs . Heat alters .. antidepressants ... female hormone replacement therapy ... and blood pressure meds. If you take any of these, you definitely need to supplement with CoQ-10.*When shopping, labels may read “CoQ-10” or “Coenzyme Q-10”, but the enzymemore active form will be labeled “QH” or “ubiquinol.” This is a stronger form of CoQ-10, making it less effectivethough purchasing that version isn’t essential, especially if price is an issue.Take 100 mg two or three times twice per day, because your body can’t metabolize higher doses.==Recommended Products==[[File:Super-ubiquinol-coq10-life-extension 2.jpg|150px|link=https://www.lifeextension.com/vitamins-supplements/item01733/super-ubiquinol-coq10-with-pqq]]
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