* [[Alpha lipoic acid]] : A 2007 study published in the Journal of Neural Transmission found alpha-lipoic acid “dramatically lowers” disease progression in Alzheimer’s disease patients who received 600 mg a day for 12 months.
*[[Vitamin B]]-Complex : A 2011 study published in the International Journal of Geriatric Psychiatry found B-complex to slow cognitive and clinical decline in people with mild cognitive impairment. The researchers noted that homocysteine is a risk factor for AD and that B vitamins may slow brain atrophy by suppressing homocysteine accumulation. [v]
*[[Alpha-GPC ]] : A 2003 study published in the journal Clinical Therapeutics found that the cholinergic precursors [[choline]] and [[lecithin]] (phosphatidylcholine) in the form of choline alfoscerate (Alpha-GPC), and naturally found in neuronal membranes, was tolerable and effective in the treatment of the cognitive symptoms of dementia disorders of the Alzheimer type.
*[[Saffron]] : A 2009 study published in the journal Psychopharmacology found that 22-weeks of saffron supplementation compared favorably to Aricept in the treatment of mild-to-moderate Alzheimer’s disease.