==Special Precautions of Apples==
* Allergy to apricot and related plants: Apple may cause an allergic reaction in people who are sensitive to the Rosaceae family. Members of this family include apricot, almond, plum, peach, pear, and strawberry. If you have allergies, be sure to check with your healthcare provider before taking apple.
* Here are some disturbing apple facts you should keep in mind when shopping...The USDA tested 700 different apple samples and found residues of at least one type of pesticide on 98% of them. 92% of apples contained pesticides even after being washed and peeled. After being sprayed with pesticides in the orchards, just-picked conventional apples are given another round of pesticide treatment to maintain their eye-appeal and to extend their shelf life.
* Apples are stored for months in supermarkets’ cold storage; during that time, their nutritional value decreases and they also lose flavor and crispness.Conventional apples also contain nitrates, the same cancer-causing preservative found in bacon, cold cuts, and pepperoni.Besides cancer, pesticide exposure has been linked to Parkinson’s, brain damage, ADHD, and lower intelligence.
* The apple seeds, contain cyanide and are poisonous. Eating enough seeds (in one case, one cup of apple seeds) can cause death. The cyanide is released in the stomach as the seeds are digested, so it may take several hours for the symptoms of poisoning to appear.
* Fexofenadine (Allegra) interacts with apple.
==The benefits of (organic or bio) Apples are==
*An apple a day, keeps the doctor away. This adage is true since apples are very rich in polyphenols, antioxidants that are beneficial in lowering the risk of inflammation and cancers.
**Breast Cancer: apples have been found to both prevent and to suppress mammary cancers in the animal model.
**Multi-Drug Resistant Cancer: carotenoids extracted from apple have been found to inhibit drug resistant cancer cell line proliferation.
**[[Esophageal Cancer]]: An apple-derived procyanidin has been found to suppress esophageal cancer.**[[Stomach Cancer]]: One of the ways in which apple constituents prevent stomach cancer is through their inhibition of Helicobacter pylori, one of the main infectious agents linked to both ulcer and gastric cancer. But apple procyanidin has also been studied for its ability to directly induce programmed cell death within stomach cancer cells.** [[Colon Cancer]] : pectin and other fibers Oligosaccharides from apples killed up to 46 percent of human colon cancer cells in vitro,
* Apples are low in calories. Only 50 calories are gained in 100-gram fresh apple slices, lower compared to other fruits and food choices. A study showed that people who ate a fresh apple 15 minutes before eating lunch consumed approximately 190 lesser calories compared to what they would consume without eating apple prior to eating meals. This proves that eating apples before meal would be a great way in reducing calorie intake.
* apple peel contains ursolic acid which can reduce obesity, pre-diabetes, and fatty liver disease.
*Periodontal Disease: We all know the sensation that follows eating an apple – that astringent property, where our gums feel squeaky clean. This is due, in part, to quercetin, which is found in apples, tea and onions, for example. It bears significant antimicrobial properties Apple polyphenol also protects against periodontal ligament cell destruction associated with Porphyromonas gingivalis, a pathogenic anaerobic bacteria, infection.[xxiv]
*Advanced Glycation End-products (AGEs): AGEs are associated with the oxidation of blood sugars, primarily. These sugars becomes caramelized when exposed to oxidants, and then binds to cell structures, e.g. fats/proteins, causing damage. Apple leaves have been found to have significant anti-AGE activity, including the vasoconstriction associated with AGE-induced endothelial dysfunction.
*[[Hair Loss]]: Remarkably, a procyanidin, labeled B-2, from apples promotes hair growth, in the cell model.
*Staphylococcal Infections: Apple pectin has been shown to inhibit synthesis of types A and B staphylococcal enterotoxins, which can cause profound bodily damage.
*[[Influenza ]] Infection: Over 60 years ago researchers found that the complex carbohydrates that make up apple pectin inhibit the infectivity of influenza A virus in chicken blood, as well in embryonated eggs, indicating its potential anti-influenza properties.
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