*Fluid retention (edema): Avoid using phosphate salts that contain sodium if you have cirrhosis, heart failure, or other conditions that can cause edema.
*High levels of calcium in the blood (hypercalcemia): Use phosphate salts cautiously if you have hypercalcemia. Too much phosphate could cause calcium to be deposited where it shouldn’t be in your body.
*High levels of phosphate in the blood: People with [[Addison's diseaseDisease]], severe heart and lung disease, kidney disease, thyroid problems, or liver disease are more likely than other people to develop too much phosphate in their blood when they take phosphate salts. Use phosphate salts only with the advice and ongoing care of a healthcare professional if you have one of these conditions.
*Kidney disease: Use phosphate salts only with the advice and ongoing care of a healthcare professional if you have kidney problems.
* Bisphosphonates interacts with PHOSPHATE SALTS