*Side effects can include skin irritation, burning, and itching. Capsicum can also be extremely irritating to the eyes, nose, and throat. Don't use capsicum on sensitive skin or around the eyes.
*Capsicum extract is LIKELY SAFE for most adults when taken by mouth, short-term and in amounts typically found in food. Side effects can include stomach irritation and upset, sweating, flushing, and runny nose. It is POSSIBLY UNSAFE to take capsicum by mouth in large doses or for long periods of time. In rare cases, this can lead to more serious side effects like liver or kidney damage.
* cancer Cancer : Conflicting epidemiologic data and basic research study results suggest that capsaicin can act as a carcinogen or as a cancer preventive agent. Long-term topical application of capsaicin increased skin carcinogenesis in mice treated with a tumor promoter.
*Capsicum extract is POSSIBLY SAFE when used in the nose. No serious side effects have been reported, but application in the nose can be very painful. Nasal application can cause burning pain, sneezing, watery eyes, and runny nose. These side effects tend to decrease and go away after 5 or more days of repeated use.
*Pregnancy and breast-feeding: Capsicum is LIKELY SAFE when applied to the skin during pregnancy. But not enough is known about its safety when taken by mouth. Stay on the safe side and don’t use capsicum if you are pregnant.