* Lipid profile : The effect of hydroalcoholic extract and essential oil of Heracleum persicum (Apiaceae) on lipid profile of male hyperlipidemic rabbits was investigated. These findings suggest that essential oil of the plant fruits may have some benefits in reducing cardiovascular risk factors.
* Infertility : The effects of the golpar plant on ovarian tissue and folliculogenesis was investigated. The results showedin vivo effects of the HPHE on the ovarian follicles of the female Wistar rat. Besides, the results suggest that administration of HPHE may have inhibitory effects on folliculogenesis and cause infertility in females.
* Anti-inflammatory and analgesic properties : The anti-inflammatory and analgesic effects of the hydroalcoholic extract and essential oil of the plant fruits andanalyzing the essential oil was evaluated. The results clearly show the analgesic and antiinflammatory anti inflammatory effects of the plant essential oil and hydroalcoholic extract. Further studies are needed to clarify the mechanism of action and the components responsible for these pharmacological effects.
* Anticonvulsant : The anticonvulsant activity of acetone extract of the seeds of Heracleum persicum (Umbelliferae) was examined against pentylenetetrazole. The extract showed a dose-dependent protective effect in both seizure models. However, the sedative dose of the extract, examined by rotarod test, was close to the anticonvulsant doses. Preliminary phytochemical analysis showed the presence of alkaloids, terpenoids, triterpenes and steroids in the extract. The observed pharmacological effects could be due to alkaloids, terpenoids and triterpenes present in the plant.