==Benefits and uses of Brucea Javanica are==
For several millennia, herbal preparations and natural remedies from B. javanica have been shown to be effective in treating many types of maladies including malaria, and amoebiasis as well as cancer. B. javanica contains alkaloids (brucamarine, yatanine), glycosides/quassinoids (brucealin, yatanoside A and B, kosamine, bruceantin, bruceantarin, bruceantinol), and phenol (brucenol, bruceolic acid). The seeds contain brusatol and bruceine. The pulp oil contains fat, oleic acid, linoleic acid, stearic acid, and palmitoleic acid. Fruit and leaves contain tannin.
* The roots and fruits are used against diarrhoea, dysentery and fevers.
* The crushed leaves are used medicinally against ring worms, scurf, boils, centipede bites and internal pains.
* Cancer :
**To date, 153 compounds have been reported from the seeds and aerial parts of Brucea javanica. Quassinoids are the main constituents of this species. The extract of Brucea javanica and the isolated compounds, specifically quassinoids exhibit various biological properties and are well known for their antitumor effects, especially how they are selectively toxic to cancer cells.
**Yet another study in the International Journal of Molecular Medicine, demonstrated the antiproliferative and apoptotic activities of B. javanica along with other herbal traditional Chinese medicines. They concluded that the programmed cell death of cancer cells activated by specific proteins was 5 times higher in cells treated with B. javanica.
**Bruceantin, a contituent of B. javanica has also been found to interfere with the growth of leukemia, lymphoma, and myeloma cells.
== References ==
[[Category:Treatments]]
[[Category:herbal medicine]]