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Cannabinoids

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Cannabis is not More than 400 active compounds have been isolated from the only C sativa plant that contains medically beneficial . Sixty active compounds are unique to the plant and are collectively known as cannabinoids. Delta-9-tetrahydrocannanbinol (THC) is the most psychoactive cannabinoid, although it has driven producing euphoria, relaxation, intensification of ordinary sensory experiences, perceptual alterations, diminished pain, and difficulties with memory and concentration.==Special Precautions of Cannabinoids==* Acute cannabis toxicity results in difficulty with coordination, decreased muscle strength, decreased hand steadiness, postural hypotension, lethargy, decreased concentration, slowed reaction time, slurred speech, and conjunctival injection. * Large doses of THC may produce confusion, amnesia, delusions, hallucinations, anxiety, and agitation, but most episodes remit rapidly. Long-term users may experience paranoia, panic disorder, fear, or dysphoria. * There is little evidence on the research extent of risk for adverse cardiovascular outcomes among cannabis users with pre-existing conditions.* See also : [[Cannabis Sativa]]==Health benefits and uses of Cannabinoids==Cannabis preparations have been used to understand the powerful therapeutic properties relieve nausea, improve appetite and reduce pain for thousands of these plant compoundsyears. In actualityThe development of synthetic drugs in the 20th century supplanted these and other herbal remedies, there are but in the past several plants decades there has been a resurgence of interest in using cannabis and cannabinoid preparations for medical purposes. * There is evidence from controlled trials that cannabinoids are also rich effective in cannabinoids relieving nausea and benefit vomiting, alleviating acute pain and improving appetite in people with HIV-related disorders. In 2001, the body’s endocannabinoid systemCanadian government responded to demands to allow medical use of smoked cannabis, which is responsible for helping if authorized by a doctor, among patients experiencing severe symptoms related to cancer, HIV infection, multiple sclerosis and epilepsy. Symptoms include nausea, pain, weight loss and persistent muscle spasms and seizures. This decision was made in the body maintain internal balanceabsence of strong evidence supporting the efficacy of cannabinoids in many of these applications.* A number of synthetic cannabinoids (e.g., or homeostasisdronabinol) have been approved for medical use in Canada, which is needed the United Kingdom and the United States. More recently, a cannabis extract (Sativex) has been provisionally approved in Canada for attaining optimum healththe treatment of multiple sclerosis.Not all patients have found that the drugs relieve their symptoms, primarily because they find it difficult to control the desired dose of orally administered cannabinoids.* See also : [[Cannabis Sativa]]
==Plant Sources of Cannabinoids==Cannabis is not the only plant that contains medically beneficial cannabinoids, although it has driven the research to understand the powerful therapeutic properties of these plant compounds. In actuality, there are several plants that are also rich in cannabinoids and benefit the body’s endocannabinoid system, which is responsible for helping the body maintain internal balance, or homeostasis, which is needed for attaining optimum health. To expand our understanding of cannabinoids and the endocannabinoid system, scientists and botanists are exploring the prevalence of cannabinoids in many plants used in natural remedies, other than just cannabis. Below are six plants found to either contain healing cannabinoids or affect the endocannabinoid system, and some of their known therapeutic benefits.* [[Cannabis Sativa]]* [[Cannabis Indica]]* [[Echinacea]], Coneflower : This plant is well-known for its ability to help the body fight off the common cold. It is also used to relieve anxiety, fatigue, migraines, and arthritis. Echinacea is a bit different than cannabis because it uses cannabimimetics instead of cannabinoids to engage the endocannabinoid system, particularly the CB2 receptor. Similar to THC in cannabis, the N-alkyl amides (NAAs) in echinacea are responsible for regulating the immune system, pain and inflammation.* [[Spilanthes]], Acmella oleracea,Electric Daisy : Native to the Amazon region, the electric daisy is used to create a painkilling gel. It successfully blocks pain receptors at nerve endings, as per trials conducted by Cambridge University. The compounds found the the electric daisy are called N-Isobutylamides, and similarly to other connabinoid-like compounds they regulate pain and inflammation. This natural remedy is emerging as a dental remedy for ailments such as impacted wisdom teeth.
* Coneflower – [[File:EchinaceaHelichrysum umbraculigerum]]This plant is well-known for its ability to help the body fight off the common cold. It is also used : Native to relieve anxiety, fatigue, migrainesSouth Africa, this daisy has a strong mood-stabilizing and arthritis. Echinacea is anti-depressant affect due to a bit different than cannabis because it uses cannabimimetics instead large amounts of cannabinoids to engage the endocannabinoid systemcannabigerol (CBG), particularly also found in the CB2 receptorcannabis plant. Similar to THC in cannabis, Helichrysum has been studied by Italian natural product chemist Giovanni Appendino. He presented at the NInternational Cannabinoid Research Society his discovery that cannabinoid-alkyl amides (NAAs) in echinacea like compounds are responsible for regulating the immune systemmade by plants, pain and inflammation.* Electric Daisy – Acmella oleraceaNative to the Amazon regionstarting from an aromatic acid, which is different from the electric daisy normal cannabinoid biosynthtic route. Helichrysum is used in African ritual ceremonies to create make fumes with a painkilling gel. It successfully blocks pain receptors at nerve endings, as per trials conducted by Cambridge University. The compounds found the the electric daisy are called N-Isobutylamides, and similarly potential psychotropic effect similar to other connabinoid-like compounds they regulate pain and inflammation. This natural remedy is emerging as a dental remedy for ailments such as impacted wisdom teethcannabinoids.
* Helichrysum umbraculigerum Liverwort, [[Radula marginata]] : Native to South AfricaThis plant, this daisy has a strong mood-stabilizing and anti-depressant affect due indigenous to a New Zealand, contains large amounts of cannabigerol (CBG)perrottetinenic acid, which is strikingly similar to THC, also found in the psychoactive component in cannabis plant. Helichrysum has been studied by Italian natural product chemist Giovanni Appendino. He presented at It is believed to bind with the International Cannabinoid Research Society his discovery that cannabinoid-like compounds are made by plantsCB1 receptors, starting from an aromatic acidjust as THC, which although liverwort is different from the normal cannabinoid biosynthtic routenot known to have any psychoactive effects. Helichrysum What it is known for is its ability to treat bronchitis, and historically it has been used in African ritual ceremonies to make fumes with a potential psychotropic effect similar to other cannabinoidsalleviate gallbladder, liver, and bladder problems.
* Liverwort – Radula marginataThis plant[[Cacao]], indigenous Theobroma cacao : The cacao plant has many therapeutic properties and it is known to New Zealandbe a powerful, contains large amounts of perrottetinenic acidand delicious superfood. Cacao affects with the endocannabinoid system by deactivating the enzyme called FAAH, which typically breaks down the endocannabinoid known as anandamide. Since anandamide is strikingly similar identified to be the body’s natural version of THC, eating natural chocolate increases the psychoactive component amounts of anandamide in cannabisthe brain because the FAAH enzyme is less active. It The result is believed similar to bind with what many people experience when smoking cannabis – a general feeling of being relaxed and happy – although the CB1 receptors, just result is nowhere near as potent as with THC, although liverwort is not known to have any psychoactive effects. What it is known for is its ability Researchers at the Neurosciences Institute of San Diego were able to treat bronchitis, and historically it has been used to alleviate gallbladder, liver, and bladder problems.back up the claims that chocolate does contain three compounds that act as healing cannabinoids
* Cacao – Theobroma cacaoThe cacao plant has many therapeutic properties and it is known to be a powerful, and delicious superfood. Cacao affects with the endocannabinoid system by deactivating the enzyme called FAAH, which typically breaks down the endocannabinoid known as anandamide. Since anandamide is identified to be the body’s natural version of THC, eating natural chocolate increases the amounts of anandamide in the brain because the FAAH enzyme is less active. The result is similar to what many people experience when smoking cannabis – a general feeling of being relaxed and happy – although the result is nowhere near as potent as with THC. Researchers at the Neurosciences Institute of San Diego were able to back up the claims that chocolate does contain three compounds that act as healing cannabinoids * [[Black Pepperpepper]] , Piper nigrum: A very common aroma molecule or terpene, called beta-caryophyllene (BCP), found in plant essential oils and abundantly present in black pepper, has been discovered to function as a cannabinoid. Similar to other plant-based cannabinoids, BCP binds with the CB2 receptors, giving it the therapeutic effect of reducing inflammation. Various research has suggested that BCP could be used for the treatment of arthritis and osteoporosis, and may potentially increase the effectiveness of certain anti-cancer drugs.[[Category:Treatments]][[Category:herbal medicine]]
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