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Other Names: Devadhupa, Balsamodendrum wightii, Balsamodendrum mukul, Commiphora mukul, Commiphora wightii, Gomme Guggul, Gomme-Résine de Guggul, Guggal, Guggul Gum Resin, Guggul Lipids, Guggulipid, Guggulipide, Guggulu, Guggulu Suddha, Guggulsterone, Guggulstérone, Guggulsterones, Guggulstérones, Guglipid, Gugulipid, Gum Guggal, Gum Guggulu, Indian Bdellium, Indian Bdellium-Tree, Koushika, Mukul Myrrh Tree, Palankasha, Yogaraj Guggul Gum Resin.<br>A yellowish resin secreted by the mukul myrrh tree (Commiphora mukul), guggul has been used for thousands of years in ayurveda (the traditional medicine of India). <br>See also : [[Myrrh]]<br>

Although it's generally considered safe, guggul extract *Guggul is POSSIBLY SAFE for most people. It has been used safely in clinical trials for up to 24 weeks. Some evidence also suggests that long-term use up to 75 weeks may trigger be safe.*It can cause side effects like headachesuch as stomach upset, headaches, nausea, vomiting, loose stools, diarrhea, belching, and hiccups. Guggul can also cause allergic reactions such as rash and itching. Guggul can also cause skin irritation (usually in the form of a rash) in and itching that is not related to allergy. These adverse reactions are more common with higher doses, such as 6000 mg per day.*Pregnancy and breast-feeding: Guggul is LIKELY UNSAFE during pregnancy. It seems to encourage menstrual flow and stimulates the uterus, so some individualsresearchers worry that it might endanger the pregnancy. Since Not enough is known about the safety of using guggul has also been found to stimulate during breast-feeding. Don’t use guggul if you are pregnant or breast-feeding.*Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Guggul might act like estrogen in the thyroidbody. If you have any condition that might be made worse by exposure to estrogen, anyone don’t use guggul.*Underactive or overactive thyroid (hypothyroidism or hyperthyroidism): Guggul might interfere with treatment for these conditions. If you have a thyroid condition should consult a physician before using , don’t use guggul extractwithout your healthcare provider’s supervision.In a 2004 study, scientists discovered that guggulsterone may inhibit *Surgery: Guggul might increase the action risk of drugs that are metabolized by bleeding during and after surgery. Stop using guggul at least 2 weeks before a scheduled surgery.* Estrogens interacts with GUGGUL : Large amounts of guggul might theoretically increase the body's CYP3A enzymesside effects of estrogen. These * Birth control pills (Contraceptive drugs include Lipitor) interacts with GUGGUL* Diltiazem (Cardizem, cyclosporineDilacor, and quinidine.Tiazac) interacts with GUGGUL* Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GUGGUL* Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GUGGUL* Propranolol (Inderal) interacts with GUGGUL* Tamoxifen (Nolvadex) interacts with GUGGUL* Thyroid hormone interacts with GUGGUL 

*Practitioners of ayurvedic medicine often blend guggul extract with other natural substances to heal health problems such as arthritis, hemorrhoids, This ancient herb contains several bioactive components that fight inflammation. Two highly effective compounds are gugglesterone and urinary tract infectionsmyrrhanol A. *Treating some types of acne. Guggul is also touted as a remedy for acne, seems to work about as well as a weight-loss stimulant.*Guggul for High Cholesterol : Although guggul is widely used the antibiotic tetracycline in India to combat high cholesterol, research on the extract's cholesterol-lowering effects has yielded mixed resultstreatment of nodulocystic acne. A 2009 study of 43 adults with moderately high cholesterolBoth treatments decrease pain, for instanceswelling , found that those who took 2and redness (inflammation),160 mg and the number of guggul acne outbreaks.* Lowering cholesterol and triglycerides in capsule form daily had the blood of people eating a greater drop Western diet. Interestingly, guggul does seem to work in total cholesterol levels than those Indian populations, who took eat a placebo pilldifferent type of diet. HoweverAmong this group, the study members who used guggul showed no significant reduction in their levels of seems to lower total cholesterol, “bad cholesterol” (LDL ("bad") cholesterol.Another study (published in 2003) assigned 103 adults with high cholesterol to take 1,000 mg or 2,000 mg of guggul daily for eight weeks, and found that the extract actually raised levels of LDL cholesterolother blood fats called triglycerides.* Arthritis. Preliminary research clinical evidence suggests that taking 500 mg of guggul extract may help fight tumors(containing 3. One 2007 study on human cells found that guggulsterone (a compound found in guggul5% guggulsterones) induced the death of [[Prostate Cancer]] cells, while a 2008 report revealed that guggulsterone thwarted the growth of skin tumors in micethree times daily might improve arthritis pain.