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Guggul

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See also Other Names: [[Devadhupa, Balsamodendrum wightii, Balsamodendrum mukul, Commiphora mukul, Commiphora wightii, Gomme Guggul, Gomme-Résine de Guggul, Guggal, Guggul Gum Resin, Guggul Lipids, Guggulipid, Guggulipide, Guggulu, Guggulu Suddha, Guggulsterone, Guggulstérone, Guggulsterones, Guggulstérones, Guglipid, Gugulipid, Gum Guggal, Gum Guggulu, Indian Bdellium, Indian Bdellium-Tree, Koushika, Mukul Myrrh]]Tree, Palankasha, Yogaraj Guggul Gum Resin.<br>A yellowish resin secreted by the mukul myrrh tree (Commiphora mukul), guggul has been used for thousands of years in ayurveda (the traditional medicine of India). <br>See also : [[Myrrh]]<br>
==Special Precautions of Guggul==
Although it's generally considered safe, guggul extract *Guggul is POSSIBLY SAFE for most people. It has been used safely in clinical trials for up to 24 weeks. Some evidence also suggests that long-term use up to 75 weeks may trigger be safe.*It can cause side effects like headachesuch as stomach upset, headaches, nausea, vomiting, loose stools, diarrhea, belching, and hiccups. Guggul can also cause allergic reactions such as rash and itching. Guggul can also cause skin irritation (usually in the form of a rash) in and itching that is not related to allergy. These adverse reactions are more common with higher doses, such as 6000 mg per day.*Pregnancy and breast-feeding: Guggul is LIKELY UNSAFE during pregnancy. It seems to encourage menstrual flow and stimulates the uterus, so some individualsresearchers worry that it might endanger the pregnancy. Since Not enough is known about the safety of using guggul has also been found to stimulate during breast-feeding. Don’t use guggul if you are pregnant or breast-feeding.*Hormone-sensitive condition such as breast cancer, uterine cancer, ovarian cancer, endometriosis, or uterine fibroids: Guggul might act like estrogen in the thyroidbody. If you have any condition that might be made worse by exposure to estrogen, anyone don’t use guggul.*Underactive or overactive thyroid (hypothyroidism or hyperthyroidism): Guggul might interfere with treatment for these conditions. If you have a thyroid condition should consult a physician before using , don’t use guggul extractwithout your healthcare provider’s supervision.In a 2004 study, scientists discovered that guggulsterone may inhibit *Surgery: Guggul might increase the action risk of drugs that are metabolized by bleeding during and after surgery. Stop using guggul at least 2 weeks before a scheduled surgery.* Estrogens interacts with GUGGUL : Large amounts of guggul might theoretically increase the body's CYP3A enzymesside effects of estrogen. These * Birth control pills (Contraceptive drugs include Lipitor) interacts with GUGGUL* Diltiazem (Cardizem, cyclosporineDilacor, and quinidine.Tiazac) interacts with GUGGUL* Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with GUGGUL* Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with GUGGUL* Propranolol (Inderal) interacts with GUGGUL* Tamoxifen (Nolvadex) interacts with GUGGUL* Thyroid hormone interacts with GUGGUL 
==The benefits of Guggul are==
This ancient herb contains several bioactive components that fight inflammation. Two highly effective compounds are gugglesterone and myrrhanol A.*Practitioners Treating some types of ayurvedic medicine often blend guggul extract with other natural substances acne. Guggul seems to heal health problems such work about as arthritis, joint well as the antibiotic tetracycline in the treatment of nodulocystic acne. Both treatments decrease pain, hemorrhoidsswelling , and urinary tract infectionsredness (inflammation), and the number of acne outbreaks. *Guggul is also touted as a remedy for acne* weight-loss : using guggul during combined weight training Lowering cholesterol and aerobic exercise increases weight loss.*Guggul for High Cholesterol : Although guggul is widely used triglycerides in India to combat high cholesterol, research on the extract's cholesterol-lowering effects has yielded mixed resultsblood of people eating a Western diet. A 2009 study of 43 adults with moderately high cholesterolInterestingly, for instanceguggul does seem to work in Indian populations, found that those who took 2eat a different type of diet. Among this group,160 mg of guggul in capsule form daily had a greater drop in seems to lower total cholesterol levels than those who took a placebo pill. However, the study members who used guggul showed no significant reduction in their levels of “bad cholesterol” (LDL ("bad") cholesterol.Another study (published in 2003) assigned 103 adults with high cholesterol to take 1,000 mg or 2,000 mg of guggul daily for eight weeks, and found that the extract actually raised levels of LDL cholesterolother blood fats called triglycerides.* Arthritis. Preliminary research clinical evidence suggests that taking 500 mg of guggul extract may help fight tumors(containing 3. One 2007 study on human cells found that guggulsterone (a compound found in guggul5% guggulsterones) induced the death of [[Prostate Cancer]] cells, while a 2008 report revealed that guggulsterone thwarted the growth of skin tumors in micethree times daily might improve arthritis pain.
*Other research shows that guggul extract may help reduce symptoms of [[osteoarthritis (OA)]] of the knee.
* Weight loss. There is some clinical evidence that guggul in combination with phosphate, hydroxycitric acid, and L-tyrosine plus exercise and a low-calorie diet might result in modest weight loss. However, a separate study of a standardized guggul extract generally used for lowering cholesterol found that doses of 3000 or 6000 mg daily for 8 weeks had no effect on body weight.
* Cancer : Preliminary research suggests that guggul extract may help fight tumors. One 2007 study on human cells found that guggulsterone (a compound found in guggul) induced the death of [[Prostate Cancer]] cells, while a 2008 report revealed that guggulsterone thwarted the growth of skin tumors in mice. Guggulsterone is confirmed to be a cancer stem cell killer. Cancer stem cells are largely responsible for the failure of conventional cancer treatment.
==Used in Patent medicine==
* [[Chandraprabha Vati]]
[[Category:Treatments]]
[[Category:herbal medicine]]
[[Category:Ayurveda]]
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