* [[Diabetes]]: A study published in 2011 in the Clinical Journal of Nutrition showed that sesame oil improved the effectiveness of the oral antidiabetic drug glibenclamide in type 2 diabetic patients. Another study published in 2006 in the Journal of Medicinal Foods showed that the substitution of sesame seed oil as the sole edible oil lowers blood pressure and glucose in hypertensive diabetics.
*[[High Blood Pressure]]: A study published in 2006 in the Yale Journal of Biological Medicine showed that sesame seed oil has a beneficial effect in hypertensive patients on either diuretics or beta-blockers. Substitution of all dietary oils with sesame oil brought down systolic and dystolic blood pressure to normal, in addition to decreasing lipid peroxidation (bodily rancidity) and antioxidant status. One of the compounds identified behind sesame seed’s antihypertensive effects are peptides that act as angiotensin I-converting enzyme inhibitors. Testing reveals the seeds contain sesamin and sesamolin, two unique varieties of lignans, substances known to reduce cholesterol and prevent high blood pressure.
* [[Gingivitis]] / [[Dental Plaque]]: Sesame seed oil has been used for oral health for thousands of years in the traditional Indian medical tradition known as Ayurveda in a process known as “oil pulling.” It involves swishing sesame seed oil in the mouth for prolonged durations and has been said to prevent teeth decay, halitosis, bleeding gums, dry throat, and for strengthening the teeth, gums and jaw. Clinical research now confirms that it compares favorably to chemical mouthwash (chlorhexidine) in improving plaque-induced gingivitis,and that it is capable of reducing Streptococcus mutans growth associated with oral plaque formation.
*Infant Health/Massage Oil: A study published in the Indian Journal of Medical Research in 2000 showed that massaging infants with sesame oil improved both their growth and post-massage sleep, in comparison to control oils such as mineral oil.
*[[Multiple Sclerosis (MS)]]: In the animal model of MS, also known as experimental autoimmune encephalomyelitis, sesame seed oil protects mice from developing the disease by reducing IFN-gamma secretion, a key factor in initiating autoimmune inflammation and injury in the nervous system. It has also been research for its potential beneficial role in another neurodegenerative condition, Huntington’s disease.