Bruhati

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Other Names : Solanum indicum, Brihati, Kateli, Jangli bhata, Bari kateri
Whole plant is used, especially roots and fruits

Special Precautions of Bruhati

Properties

bitter, acrid, astringent, carminative, stomachic, resolvent, demulcent, diuretic, emmenagogue, febrifuge, and cardiotonic.

Health Benefits and Uses of Bruhati

Whole plant of Indian Nightshade is used for cardiac tonic, astringent, carminative, immunomodulator agent and clinically uses for weakness, nausea and bronchospasm (Sultana et al., 2011). S. indicum fruits stimulate and strengthen the heart and ameliorate the oedema. It also works well in dysuria and urinary calculi (Chopra et al., 1992; Kirtikar and Basu, 1975).

  • treatment of asthma
  • catarrh
  • dropsy
  • chest pain
  • chronic fever
  • colic,
  • dry and spasmodic cough
  • oedema
  • scorpion stings
  • difficult urination
  • worm infestation.
  • Antibacterial activity Ethanolic extract of leaves of S. indicum showed antibacterial activity against Corynebacterium diptheriae, Pseudomonas spp., and Salmonella typhimorium (Gavimath et al., 2012) Staphylococcus aureus, Bacillus cereus, Escherichia coli (Srividya et al., 2009) where as chloroform extract, acetone extract and ethanol extract also showed anti bacterial activity against pseudomonas (Srividya et al., 2009). S. indicum fruits also possess antibacterial activity. Aqueous and ethanolic extracts extracts were found to be effective against Listeria innocua, S. aureus, E. coli and P. aeruginosa strains.
  • Antioxidant activity
  • Number of Indiosides (A to E) isolated from S. indicum have dose-dependent inhibitory effect on proliferation of Bel7402 cells, and can induce cell apoptosis through mitochondria-dependent pathway (Ma et al., 2006.). Solavetivone-1, a component of S. indicum exhibited cytotoxicity to OVCAR-3 cells (Syu et al., 2001). The anticancer activities of S. indicum (whole plant) chloroform soluble and insoluble fractions of the ethanolic extract were determined by using in-vitro techniques and showed cytotoxicity on seven cancer cell lines: Colo-205 (colon), KB (nasopharynx), HeLa (uterine cervix), HA22T (hepatoma), Hep-2 (laryngeal epidermoid), GBM8401/TSGH (glioma) and H1477 (melanoma).
  • Gastric Ulcers : The anti-ulcerogenic effects of the methanolic extract of S. indicum var. distichum fruit has been investigated on aspirin and ethanol induced ulceration in rats. The extract not only protects gastric mucosa from damaging effect of aspirin as well as ethanol but also promotes healing of the ulcer.
  • CNS depressant activity The spontaneous locomotor activity of adult wistar albino rats was evaluated after the administration of methanolic extract of fruit. The extract (500 mg/kg) exhibited maximum locomotor inhibitory activity after 1 hr. CNS depressant activity of drug was found to be significantly better than the standard drug diazepam (0.5 mg/kg) (Deb et al., 2014).

Used in Patent medicine

References

https://www.researchgate.net/publication/320331018_Solanum_indicum_Linn_An_ethnopharmacological_phytochemical_and_pharmacological_review