Metabolic Therapy

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When the term metabolic therapy is used by doctors of alternative medicine, it denotes, not a specific therapy, but a category of treatments which are non-toxic, non-invasive, and which support the anabolic process. Metabolic therapy uses a combination of special diets, enzymes, nutritional supplements, and other measures in an attempt to remove "toxins" from the body and strengthen the body's defenses against disease. Metabolic therapy is based on the belief that toxic substances in food and the environment build up in the body and create chemical imbalances that lead to diseases such as cancer, arthritis, and multiple sclerosis. Some proponents of this approach say that metabolic therapy rids the body of these toxins and strengthens its resistance to disease. Some claim that a special diet can cure serious illnesses, including cancer. Others claim that they can evaluate a patient's metabolism and diagnose cancer before symptoms appear and that they can locate tumors and learn the tumor's size and growth rate. Metabolic therapies vary a great deal depending on the practitioner, but all are based on special diets and detoxification. This usually involves natural, whole foods such as fresh fruits and vegetables, as well as vitamins and mineral supplements. Other measures may include colonic irrigation with coffee or hydrogen peroxide enemas, juicing, enzyme supplements, visualization, and stress-reduction exercises. At least one metabolic therapy system also includes the drug laetrile. Among the better known types of metabolic therapy are

  • Kelley's treatment : Dr. William Kelly and Dr. Nicholas Gonzales are well known for their use of metabolic therapy in treating cancer. Kelley's treatment includes dietary supplements (such as enzymes and large doses of vitamins, minerals, and amino acids), detoxification (such as fasting, exercising, and using laxatives and coffee enemas), a restricted diet, chiropractic adjustments, and prayer. Practitioners classify people into different metabolic types that form the basis for individual dietary and supplement recommendations. Dr. Kelly's book is online at http://www.drkelley.com/CANLIVER55.html or you can order it from Christian Cancer Volunteers at 316-290-2128.
  • The Gonzalez treatment : The Gonzalez treatment is similar to Kelley's treatment and includes extracts or concentrates from animal organs such as thymus and liver (taken from beef or lamb) and digestive enzymes as part of the plan.
  • Issels whole body therapy : Another form of metabolic therapy is Issels whole body therapy. Patients are asked to remove teeth that contain mercury dental fillings, follow a strict diet, and eliminate the use of tobacco, coffee, tea, and other substances that are considered harmful. Some patients are encouraged to undergo psychotherapy to relieve stress and deal with anger and emotional distress
  • Gerson therapy: Gerson therapy involves a strict dietary program, coffee enemas, and various mineral or chemical supplements.

Special Precautions of Metabolic Therapy

  • Consult your doctor before using any presented information as a form of treatment. Use alternative cancer treatments as a supplement to treatments you receive from your doctor — not as a substitute for medical care. Apply the treatment only under control of an expert.
  • These substances may have not been thoroughly tested to find out how they interact with medicines, foods, or dietary supplements. Even though some reports of interactions and harmful effects may be published, full studies of interactions and effects are not often available. Because of these limitations, any information on ill effects and interactions below should be considered incomplete.
  • Some aspects of metabolic therapy are considered dangerous. There are reports of complications related to liver cell injections, as well as nutritional deficiencies due to restricted diets. Several deaths have been directly linked to injecting live cells from animals (a practice called cell therapy). The drug laetrile may cause nausea, vomiting, headache, dizziness, and even cyanide poisoning, which can be fatal. Care should be taken to make sure that any diet containing raw meat or raw meat juice is free from contamination, given the increasing number of diseases that are known to be transmitted from animals to people.
  • Reports of illness and even deaths linked to colonic irrigation have been published in several medical journals. (See Colon Therapy for more information.) People with diverticulitis, ulcerative colitis, Crohn's disease, severe hemorrhoids, or rectal or colon tumors, or who are recovering from bowel surgery, may be at higher risk of bowel injury when using enemas. People with kidney or heart failure may be more likely to experience fluid overload or electrolyte imbalances. Enemas can also cause discomfort and cramps.
  • Women who are pregnant or breast-feeding should not use this method. Relying on this type of treatment alone and avoiding or delaying conventional medical care for cancer may have serious health consequences.

The benefits of Metabolic Therapy are

There is general agreement among scientists that there are differences in the metabolism of certain cells in people with cancer compared to people without cancer. There is also general agreement regarding the importance of attention to optimal nutrition as a component of conventional oncology care. Otherwise, there is no convincing clinical evidence that supports the claims made for metabolic therapy or any of its components. Some aspects of metabolic therapy may in fact be harmful.

An article on metabolic therapies on the Memorial Sloan-Kettering Cancer Center Web site concludes that "…retrospective reviews of the Gerson, Kelley, and Contreras metabolic therapies show no evidence of efficacy." And a review article in the Journal of Clinical Gastroenterology, "Colonic Irrigation and the Theory of Autointoxication," concludes that

"[c]offee enemas are a hazardous derivative of colon therapy…. Its proponents claim that caffeine is absorbed in the colon and leads to a vasodilatation in the liver, which in turn enhances the process of elimination of toxins. None of this is proved, nor is there any evidence of the clinical efficacy of coffee enemas. Coffee enemas are associated with severe adverse reactions."

In a 1990 report from the Congressional Office of Technology Assessment, 3 oncologists reviewed the "best cases" collected by Dr. Gonzalez. In the vast majority of these cases, they found claims of benefit from metabolic therapy to be unconvincing. In addition, they found a few cases to be "unusual" at best, meaning that these patients lived longer than typical people with the same type and stage of cancer but concluded that this difference was probably due to statistical variation that occurs when "best cases" are selected from a large group of patients. A group of physicians who practiced alternative medicine (none of whom were cancer specialists) concluded that the alternative regimen was beneficial in some cases.

A small study of patients with pancreatic cancer -- conducted by Dr. Gonzalez and published in Nutrition and Cancer in 1999 -- found that patients treated with pancreatic enzymes survived longer than typical patients with pancreatic cancer. In a recent review of alternative cancer cures, an expert in integrative oncology research methods noted that, "The study was small and obviously prone to several biases. Not only is the comparison with national averages unadjusted for confounders (other factors that can affect outcome), but the principal results are based on patient selection; twelve patients who did not comply with treatment were excluded from analysis." A randomized clinical trial has been sponsored by the National Cancer Institute to evaluate the Gonzalez regimen for treating pancreatic cancer, but no results of this trial have yet been published in any available peer-reviewed medical journal.

References

Medical Disclaimer

This information is not meant to be substituted for medical advice. Always consult a medical professional regarding any medical problems and before undertaking any treatment or dietary changes.