Natto

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Natto

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Nattō (なっとう or 納豆?) is a traditional Japanese food made from soybeans fermented with Bacillus subtilis.[1] It is popular especially as a breakfast food.

Special Precautions of Natto

  • Nattokinase shouldn't be used by people with bleeding disorders, or by people who are taking Coumadin (warfarin), aspirin, or any other drug that influences blood clotting (unless under doctor's supervision).
  • Nattokinase may lower blood pressure.
  • The safety of nattokinase supplements in healthy people isn't known. Use of the supplements could theoretically lead to easy bruising and excessive bleeding.
  • Natto and many nattokinase supplements contain vitamin K. Large amounts of vitamin K may decrease the effectiveness of Coumadin.
  • The safety of nattokinase in pregnant or nursing women or children is unknown.

The benefits of Natto are

Nattokinase is thought to be help dissolve abnormal blood clots. Abnormal blood clots can cause heart attacks and strokes, as well as conditions such as phlebitis, pulmonary embolism, or deep vein thrombosis.

How is Nattokinase Believed to Work?: One theory is that it dissolves the tiny fibers (fibrin) that form the strong mesh in blood clots. Streptokinase and urokinase, drugs administered intravenously after a heart attack or stroke, work the same way. Nattokinase, however, is absorbable by mouth and believed to be longer-acting.

Nattokinase is said to have similar clot-dissolving abilities as plasmin, a natural enzyme in blood. In contrast, aspirin reduces stickiness of blood cells (platelets) that, together with fibrin strands, make up blood clots. The drug Coumadin (warfarin) works on abnormal clotting by preventing fibrin strands from forming a clot.

Is There Evidence That Nattokinase Works?: There is very limited evidence that nattokinase can break up blood clots. Studies have mostly involved animals or test tube research.

There haven't been any large, well-designed studies showing that nattokinase is effective or safe in humans.

In one study, people were given nattokinase or a placebo before a long distance flight. Seven of the 92 people who took the placebo developed a clot, compared to none of those who took nattokinase. The design of the study, however, has been questioned.