Prader–Willi syndrome (PWS)

Other Names : Syndrome of hypotonia-hypomentia-hypogonadism-obesity (HHHO) Prader–Willi syndrome (PWS) is a genetic disorder due to loss of function of specific genes on chromosome 15. In newborns symptoms include weak muscles, poor feeding and slow development.

Symptoms

This syndrome effects the functions of the endocrine, cardiovascular, respiratory, muscular, and skeletal system. PWS also has a significant impact on cognitive and behavioral functioning. The symptoms can range from poor muscle tone during infancy to behavioral problems in early childhood. Some symptoms that are usually found in infants, besides poor muscle tone, would be a lack of eye coordination; some are born with almond-shaped eyes; and due to poor muscle tone the infant may not have a strong sucking reflex. Their cry is weak, and they have difficulty waking up. Another sign of this condition is a thin upper lip. More aspects seen in a clinical overview include hypotonia and abnormal neurologic function, hypogonadism, developmental and cognitive delays, hyperphagia and obesity, short stature, and behavioral and psychiatric disturbances.

Home remedies

• Healthcare providers will customize a caloric and dietary plan for PWS individuals. As a general guideline, individuals are restricted to 1,200 calories a day and meals should have a higher protein content and limited carbohydrates and complex sugars20. This ensures that the PWS individual is getting the nutrition needed and controlling the amount of sugar intake in the body, as these individuals are prone to diabetes mellitus.
• Exercise is very important for these patients, and treatment should emphasize an exercise plan. Practitioners should work with physical therapists and occupational therapists so that the physical treatment is holistic. Individuals with Prader-Willi Syndrome would benefit from starting the morning with light yoga stretches preformed at or before sunrise40. Due to the gross and fine motor restrictions found in a number of these patients, help from a caretaker may be required. The caretaker should promote as much independence as possible, but should be available in case help is needed. This will also help establish a close and intimate bond with patient and caretaker. Light walking and moderate exercise are recommended throughout the day to promote movement and strengthening of the muscles. Morning oil massages and nightly warm baths are also beneficial to help relax the mind and aid in digestion.
• Sensory therapies can also help boost cognitive functioning. Aromatherapy blends with calamus (Acorus calamus), lavender (lavendula spica), rosemary (Rosmarinus officinalis), and sandalwood (Santalum album)42. Breathing in these fragrances help clear up the channels in the mind, increase focus and perception, as well as adding warming qualities to the mind.
• Since there is no cure for Prader-Willi Syndrome, all herbal remedies for this syndrome should be given with the intention of alleviating symptoms and improving the individual’s quality of life. Calamus (Acorus calamus) root is highly beneficial for balancing all symptoms of Prader-Willi Syndrome because the properties are multisystemic. Calamus can also help with the psychological and neurological symptoms of PWS because of its slight hallucinogenic properties. However, Calamus is currently banned in the United States for internal consumption and when permitted to be sold, as topical ointment or oil, is required to be labeled “legal ecstasy.” There is a high toxicity rate with this herb and pregnant women should heed caution because it is a documented emmenagogue and abortificant.
• A herbal formula including Ashwagandha (Withania somnifera), Licorice root (Glycyrrhiza glabra), and Shatavari (Asparagus racemosus) would have a positive effect without averse side effects on any individual with PWS.

Medical Disclaimer

This information is not meant to be substituted for medical advice. Always consult a medical professional regarding any medical problems and before undertaking any treatment or dietary changes.