Suehirotake

Schizophyllum commune

Other Names : Schizophyllum commune, Split-Fold Mushroom, Common Split-gill, hed krang
Suehirotake is best known for its polysaccharide structure, schizophyllan (SPG), a polysaccharides commonly used to derive pharmaceuticals. See also :

• Beta glucan
• MGN-3

Special Precautions of Suehirotake

Infections of Schizophyllum commune have been linked to adverse health effects as brain abscess, fungus ball in the lungs, sinusitis, allergic bronchopulmonary mycosis, ulcerative lesions of the hard palate, chronic lung disease, meningitis, and onychomycosis. In one case, the fungus had grown through the soft palate of a child's mouth and was actually forming mushrooms in her sinuses.

Health Benefits and uses of Suehirotake are

Suehirotake consists of schizophyllan (SPG) which is a polysaccharide-protein complex which may help to support liver and immune health. The intracellular enzymes, ScFz, may assist in the fibrin degradation process which may help support a health blood pressure and cardiovascular wellness.

• Anti-Candida
• anti-tumor (cervical, uterine, stomach Ca)
• anti-viral
• hed krang (Schizophyllum commune) is also used in the making of fruit tea with combination of other local fruits : salak fruit, pineapple and longan. The composition of high antioxidants has driven this product development which is then optimised. The optimum formula of desired fruit tea contains the ratio of pineapple, salak, and longan of 20:20:60, respectively, added with 20% (w/w) of hed krang. Upon analysis of the chemical, physical, and microbiological properties as well as the sensory evaluation, the product seems to have great potential of acceptance by consumers and could be a power packed healthy drink.

References

• Liu et al., Immunomodulation and anti-cancer activity of polysaccharide-protein complexes., Curr Med Chem. 2000 Jul;7(7):715-29.
• Chen et al., Protease purified from Schizophyllum commune culture broth digests fibrins without activating plasminogen., Am J Chin Med. 2010;38(6):1223-31.
• Flynn et al., A potent specific inhibitor of 6-phosphogluconate dehydrogenase of Cryptococcus neoformans and of certain other fungal enzymes., Mycopathologia. 1993 Sep;123(3):155-8.
• Fujiwara et al., Cooperative role of T lymphocytes and macrophages in anti-tumor activity of mice pretreated with schizophyllan (SPG)., Jpn J Exp Med. 1982 Apr;52(2):59-65.
• Wasser SP, Weis AL., Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: a modern perspective., Crit Rev Immunol. 1999;19(1):65-96.
• Mongkontanawat, N. Product development of fruit tea mixed with ‘Hed krang’ (Schizophyllum commune). J Agric Technol 2013; 9(7): 1665-1676.