Ubiquinol

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Ubiquinol is an electron-rich (reduced) form of Coenzyme Q10

Special Precautions of Ubiquinol

  • Drugs.com notes rarely, it might cause nausea, loss of appetite, headache, gastrointestinal upset and diarrhea. It also notes some case reports of allergic reactions.
  • CoQ10 and vitamin K have a similar structure. As vitamin K promotes blood clotting, using CoQ10 at the same time as warfarin and other anticoagulant medications could antagonize their effects.
  • If you have diabetes and take insulin or other glucose-lowering medications, you might require dosage adjustments to compensate for the potential blood-sugar lowering effect of this supplement. Its potential to lower blood pressure might also require a similar course of action if you take drugs to control hypertension.
  • Some debate exists over whether antioxidant supplements interfere with the effectiveness of chemotherapy drugs. If undergoing cancer treatment, talk to your doctor before using CoQ10 or any other supplement. Memorial Sloan-Kettering Cancer Center notes animal research that suggests this supplement might interfere with the effectiveness of radiation therapy.
  • The University of Maryland Medical Center advises you to consult your pediatrician before giving CoQ10 to a child. Whether you can safely use this supplement while pregnant or breastfeeding has not been established. If you have liver or kidney disease, always clear the use of any sort of supplement with your doctor as these organs -- especially when functioning at reduced capacity -- have a particular sensitivity to what you put in your body. CoQ10 does not have any officially documented contraindications -- instances where you should not use it -- but it is always prudent to talk to your doctor about the appropriateness of using a supplement if you have any medical condition.

Benefits and uses of Ubiquinol are

Scientists have found that the ubiquinol, the reduced form of Co Q 10, dramatically improves absorption of Co Q 10 in patients with severe heart failure compared to supplements of ubiquinone, the unreduced form of Co Q 10. In other findings, the high antioxidant status of ubiquinol has allowed it to significantly inhibit inflammation. And to top it off, prices for the more effective ubiquinol have come down to levels commensurate with those of the unreduced Co Q 10 supplements in the ubiquinone form.

  • Improvements heart function in individuals with Heart Failure
  • Several health benefits for patients with Neurodegenerative Brain Disease
  • strong anti-inflammatory properties

Food Sources

In foods, there are varying amounts of ubiquinol. An analysis of a range of foods found ubiquinol to be present in 66 out of 70 items and accounted for 46% of the total coenzyme Q10 intake. The following chart is a sample of the results.

Food Ubiquinol (μg/g) Ubiquinone (μg/g)
Beef (shoulder) 5.36 25
Beef (liver) 40.1 0.4
Pork (shoulder) 25.4 19.6
Pork (thigh) 2.63 11.2
Chicken (breast) 13.8 3.24
Mackerel 0.52 10.1
Tuna (canned) 14.6 0.29
Yellowtail 20.9 12.5
Broccoli 3.83 3.17
Parsley 5.91 1.57
Orange 0.88 0.14

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